We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Detection and genetic characterization of hepatitis E virus (HEV) genotype 3 subtype c in wild boars in Italy.
- Authors
Profio, Federica; Melegari, Irene; Sarchese, Vittorio; Robetto, Serena; Marruchella, Giuseppe; Bona, Maria; Orusa, Riccardo; Martella, Vito; Marsilio, Fulvio; Martino, Barbara
- Abstract
Hepatitis E virus (HEV) was detected in stools collected from wild boars in Italy, with an overall prevalence of 1.5 % (3/196). The sequence of a ~3.0-kb portion at the 3′ end of the genome of one such strain, HEV/WB/P6-15/ITA, was determined. In the full-length ORF2, which encodes the capsid protein, the virus was genetically closest to wild boar and human HEV strains currently classified as genotype 3 subtype c. Interestingly, the 3' end of ORF2 of the WB/P6-15/ITA matched the 340-nucleotide (nt) sequence (94.0 % nt identity) of the human strain PeGe, identified in 2015 from a patient with acute hepatitis E in Genoa, Italy, suggesting that similar HEV strains are circulating in the same geographical setting in humans and animals.
- Subjects
ITALY; HEPATITIS E virus; WILD boar; VIRAL genetics; FECES examination; SWINE manure microbiology; DISEASES
- Publication
Archives of Virology, 2016, Vol 161, Issue 10, p2829
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-016-2964-y