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- Title
Bacterial Zoonotic Diseases and Male Reproduction.
- Authors
Okeleji, Lateef Olabisi; Ajayi, Lydia Oluwatoyin; Odeyemi, Aduragbemi Noah; Amos, Victor; Akanbi, Bosede Grace; Onaolapo, Moyinoluwa Comfort; Olateju, Bolade Sylvester; Adeyemi, Wale Johnson; Ajayi, Ayodeji Folorunsho
- Abstract
Simple Summary: Diseases passed from animals to humans are a big concern for public health, often making people sick or even causing death. These illnesses can also affect people's ability to have children, especially in men. Yet, we don't know much about how these diseases impact men's ability to have kids. This review looks at common animal-related diseases from bacteria and how they might affect men's fertility. Even though there's not a lot of human research in this area, studies on animals suggest these diseases could harm men's ability to have children by causing inflammation and messing up the body's natural defenses, leading to harmful substances being produced. It's important to do more research to understand how these diseases affect men's fertility so we can find ways to prevent or treat them, which would help keep people healthy and able to have families. Bacterial zoonotic diseases hold significant public health importance due to their substantial contribution to human morbidity and mortality. These infections have been implicated in reducing the fertility rate among couples of reproductive age. Despite the increasing prevalence of infertility and sub-fertility in men, there has been limited investigation into the possible effects of bacterial zoonotic infections on the male reproductive system. The purpose of this review is to describe common bacterial zoonotic diseases and their effects on human reproduction in order to unveil the hidden roles these infections could play in male factor infertility. While there is a dearth of information on this subject from human studies, available evidence from experimental animals suggests that bacterial zoonotic diseases impair male reproductive functions and structures primarily through the activation of the inflammatory response and distortion of the antioxidant system, resulting in the generation of oxidative species. In light of the limited research on bacterial zoonotic diseases and their role in male reproduction, efforts must be directed towards the subject to unravel the underlying pathological mechanisms and reduce the incidence among the human populace, either through preventive or curative measures.
- Subjects
ZOONOSES; MALE reproductive organs; PUBLIC health; INFLAMMATION; OXIDATIVE stress
- Publication
Zoonotic Diseases (2813-0227), 2024, Vol 4, Issue 1, p97
- ISSN
2813-0227
- Publication type
Article
- DOI
10.3390/zoonoticdis4010010