We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Resources available for sheep genomics research.
- Authors
Cockett, N. E.; Hadfield, T. S.; Wu, C. H.; Nomura, K.
- Abstract
Animal geneticists have been searching for the molecular basis of production traits in livestock species, including sheep, for over 40 years. Phenotypes of interest in sheep include fertility, reproduction, growth rate and efficiency, milk production, carcass quality and composition, wool characteristics, and disease resistance. The development of an ovine genome map containing molecular markers and genes has greatly advanced the identification of genetic regions containing quantitative trait loci (QTL) in sheep. Other genomic resources available for researchers investigating traits in sheep include an ovine radiation hybrid panel, large insert genomic libraries, and large-scale sequencing projects. These resources will greatly facilitate current positional cloning efforts to identify causal mutations that underlie economic trait loci. Scientists involved in sheep molecular genetics will be better able to exploit comparative information from the fully sequenced, information-rich genomes (human, mouse, and rat). These resources will also provide the scaffold for sequencing the ovine genome, a project that the sheep community is working towards for the future. In order to continue the identification of genes controlling important phenotypes in sheep, development of ovine genomic resources should continue.
- Subjects
SHEEP; GENE libraries; MOLECULAR genetics; MILK yield; NATURAL immunity; COMPARATIVE genomics; SHEEP breeding; PLANT gene mapping
- Publication
Journal of Animal Science, 2006, Vol 84, p158
- ISSN
0021-8812
- Publication type
Article