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- Title
THE TOXIC EFFECT OF ORGANIC COORDINATION COMPOUNDS IN VIVO STUDIES.
- Authors
Elena, ROŞCOV; Ion, TODERAȘ; Aurelian, GULEA; Olesea, GLIGA
- Abstract
The influence of the coordination compounds TIA-84 and TIA-86 on the viability of Paramecium caudatum ciliates was studied. The LC50 toxic effect of the organic coordination compounds TIA-84 and TIA-86 in in vivo studies was found to be 3.8 ± 0.1 μM (TIA-84) and 1.2 ± 0.02 μM (TIA-86) time for 24 h and of 3.2 ± 0.5 μM (TIA-84) and 1.0 ± 0.03 μM (TIA-86) for 48 h. The studied compound TIA-84 has shown lower toxicity comparatively to analogue TIA-86 compound.
- Subjects
ORGANIC compounds; PARAMECIUM; IN vivo studies; CILIATA
- Publication
Oltenia, Studii si Comunicari Seria Stiintele Naturii, 2023, Vol 39, Issue 1, p102
- ISSN
1454-6914
- Publication type
Article