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- Title
Effect of laser peripheral iridotomy using argon and neodymium-YAG lasers on corneal endothelial cell density: 7-year longitudinal evaluation.
- Authors
Ono, Takashi; Iida, Masaharu; Sakisaka, Toshihiro; Minami, Keiichiro; Miyata, Kazunori
- Abstract
Purpose: To evaluate the changes in corneal endothelial cell density (ECD) over a 7-year period after laser peripheral iridotomy (LPI) using argon and neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers.Study design: Retrospective case series.Methods: Eyes that underwent prophylactic LPI using argon and Nd:YAG lasers were followed up for 7 years. Central corneal endothelial cells were observed by use of noncontact specular microscopy preoperatively and at 1 and 7 years postoperatively. Changes in ECD and the associations between preoperative ECD and the total energy of the Nd:YAG laser were evaluated.Results: Fifty-one eyes of 51 patients were followed up for 7 years. The ECD significantly decreased after LPI (<italic>P</italic> < 0.049), and the reduction rate at 1 year after the surgery (1.69 ± 4.80%, 95% CI: 0.34%-3.04%) was significantly higher than the annual reduction rates after 1 year (0.17 ± 0.85%/y, <italic>P</italic> = 0.036, 95% CI: -0.07% to 0.41%). No association was found between the preoperative ECD and the total laser energy.Conclusions: Long-term evaluation indicated that the reduction in ECD after argon-Nd:YAG laser LPI was present but small during the initial year and was negligible after 1 year.
- Subjects
IRIDECTOMY; ARGON lasers; NEODYMIUM lasers; ENDOTHELIAL cells; CORNEA
- Publication
Japanese Journal of Ophthalmology, 2018, Vol 62, Issue 2, p216
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-018-0569-6