We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
ABORDAGEM INTRA E EXTRAORAL PARA EXÉRESE DE OSTEOSSARCOMA MAXILOFACIAL CANINO: RELATO DE CASO.
- Authors
HUPPES, R. R.; ALMEIDA, A. A. F.; PASCOLI, A. L.; PEREIRA, L. B. P.; GOMES, E. R.; DE NARDI, A. B.; CASTRO, J. L. C.
- Abstract
Osteosarcoma is a common mesenchymal neoplasm in dogs and humans. It can be classified as appendicular, axial or extra skeletal, depending on the type of bone or tissue involved. It predominates in appendicular bones such as the radius, humerus and femur, and can metastasize to the thorax, with rare occurrence in the jaw. Common in large, female and elderly dogs, representing 2 to 5% of malignant neoplasms. This article aimed to report a case in a 10-year-old Blue Heeler dog, complaining of sneezing with blood elimination after regression of edema in the rostral jaw. The computed tomography selected harmful bone lysis with a lytic and expansive appearance, which affected the left incisor bone, the left lateral position of the rostral third of the maxillary bone, extending to the left canine and also affecting the nasal cavity. An incisional biopsy was performed with a bone punch needle, with histopathological results of initial oral osteosarcoma. Chest radiographs in three projections revealed no metastases. The patient was referred for left hemimaxillectomy with lateral rhinotomy to remove the neoplasm and the affected bone part. The histopathological examination with free margins, however, was chosen to carry out adjuvant chemotherapy with carboplatin 250 mg/m2 every 21 days for five sessions and metronomic cyclophosphamide 15 mg/m2 every other day for six months. The removal of the mandibular lymph node and the absence of neoplastic cells confirm the slow metastasis of maxillofacial osteosarcoma. The patient survived 11 months, being euthanized due to lung metastasis. The combination of radical surgery, chemotherapy and control of prognostic markers can improve treatment results.
- Subjects
MAXILLECTOMY; CANCER chemotherapy; TUMORS
- Publication
ARS Veterinaria, 2023, Vol 39, Issue 4, p131
- ISSN
0102-6380
- Publication type
Case Study
- DOI
10.15361/2175-0106.2023v39n4p131-136