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- Title
Prospective Multicenter International Surveillance of Azole Resistance in Aspergillus fumigatus.
- Authors
van der Linden, J. W. M.; Arendrup, M. C.; Warris, A.; Lagrou, K.; Pelloux, H.; Hauser, P. M.; Chryssanthou, E.; Mellado, E.; Kidd, S. E.; Tortorano, A. M.; Dannaoui, E.; Gaustad, P.; Baddley, J. W.; Uekötter, A.; Lass-Flörl, C.; Klimko, N.; Moore, C. B.; Denning, D. W.; Pasqualotto, A. C.; Kibbler, C.
- Abstract
To investigate azole resistance in clinical Aspergillus isolates, we conducted prospective multicenter international surveillance. A total of 3,788 Aspergillus isolates were screened in 22 centers from 19 countries. Azole-resistant A. fumigatus was more frequently found (3.2% prevalence) than previously acknowledged, causing resistant invasive and noninvasive aspergillosis and severely compromising clinical use of azoles.
- Subjects
DISEASE prevalence; ASPERGILLUS fumigatus; AZOLES; HETEROCYCLIC compounds; DRUG resistance
- Publication
Emerging Infectious Diseases, 2015, Vol 21, Issue 6, p1041
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid2106.140717