We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis and antibacterial activity of 3,4-dihyhdropyrido[3′,2′:4,5]thieno[3,2- d]pyrimidin-4-ones.
- Authors
Kostenko, E.; Kaigorodova, E.; Serdyuchenko, I.; Terekhov, V.; Konyushkin, L.
- Abstract
A series of 3,4-dihydropyrido[3′,2′:4,5]thieno[3,2- d]pyrimidin-4-ones were synthesized by the reaction of ethyl 3-alkyl(aryl)carboxamidothieno[2,3- b]pyridine-2-carboxylates with aliphatic amines. The starting carboxamides were obtained via the reaction of ethyl 3-aminothieno[2,3- b]pyridine-2-carboxylate with acid chlorides. It is established that the synthesized pyridothienopyrimidinones possess antistaphylococcal activity.
- Subjects
HETEROCYCLIC compounds; PYRIDINE; ORGANIC compounds; CHLORINE compounds; ETHYL chloride
- Publication
Pharmaceutical Chemistry Journal, 2008, Vol 42, Issue 9, p533
- ISSN
0091-150X
- Publication type
Article
- DOI
10.1007/s11094-009-0168-4