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- Title
Acute coronary syndrome in a breast cancer patient treated with tamoxifen.
- Authors
Benbrahim, Zineb; Arifi, Samia; Boudahna, Lamiae; Amaadour, Lamiae; Sekkali, Naim; Lahlou, Ikram; Akoudad, Hafid; Mellas, Nawfel; El Mesbahi, Omar
- Abstract
Tamoxifen is a non-steroidal antioestrogen widely used in the treatment of breast cancer. Prolonged exposure to this therapy may result in cardio vascular undesirable events particularly thrombotic events. Arterial effects are rare. We report a case acute coronary syndrome in a locally advanced post menopausal breast cancer treated with neoadjuvant chemotherapy, surgery, adjuvant chemotherapy, radiotherapy and tamoxifen for 2 years. Then we discuss the controversial protective effect of tamoxifen against myocardial infarction.
- Subjects
BREAST cancer treatment; TAMOXIFEN; NONSTEROIDAL anti-inflammatory agents; ADJUVANT treatment of cancer; CANCER chemotherapy; RADIOTHERAPY; CORONARY heart disease prevention; MYOCARDIAL infarction
- Publication
Pan Arab Journal of Oncology, 2014, Vol 7, Issue 2, p10
- ISSN
2070-254X
- Publication type
Case Study