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- Title
Mechanical and chemical implant decontamination in surgical peri-implantitis treatment: preclinical 'in vivo' study.
- Authors
Carral, Cristina; Muñoz, Fernando; Permuy, María; Liñares, Antonio; Dard, Michel; Blanco, Juan
- Abstract
Objective The aim of the present study was to evaluate the effect of a titanium brush and chemical agents following surgical treatment of experimental peri-implantitis. Material and Methods Six implants were installed in the mandible of eight beagle dogs (unit of analysis) 3 months after tooth extraction. Experimental peri-implantitis was induced 3 months later. The defects were randomly allocated in three treatment groups: (a) TiBrush™ + sodium hypochlorite + chlorhexidine ( TBH), (b) TiBrush™ + chlorhexidine ( TB), (c) an ultrasonic device + chlorhexidine ( US). The distal implant in each hemimandible was used as control, and no treatment was done. Clinical and histological measurements were performed after 3 months of healing. Results All treatment procedures resulted in statistically significant improvements of all clinical parameters. Histomorphometrical analysis revealed no statistically significant differences between treatment groups in terms of woven bone height (primary outcome). However, there were differences between test and control groups in terms of inflammation, bone defect depth and bone refill without differences between TBH and TB groups. Conclusions Resolution of peri-implantitis after access surgery and decontamination of peri-implant surfaces with TiBrush™ with or without sodium hypochlorite is possible. However, the concomitant use of sodium hypochlorite has minor effect on treatment outcomes.
- Subjects
THERAPEUTICS; SODIUM hypochlorite; CHLORHEXIDINE; ANALYSIS of variance; ANIMAL experimentation; CHI-squared test; DEBRIDEMENT; DOGS; DENTAL implants; MANDIBLE; RESEARCH funding; STATISTICS; TITANIUM; ULTRASONICS; DATA analysis; TREATMENT effectiveness; DATA analysis software; IN vivo studies
- Publication
Journal of Clinical Periodontology, 2016, Vol 43, Issue 8, p694
- ISSN
0303-6979
- Publication type
Article
- DOI
10.1111/jcpe.12566