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- Title
Disseminated invasive Corynebacterium simulans infection complicated by high-level daptomycin resistance acquisition under treatment: a case report.
- Authors
Conquet, Guilhem; Martel, Nicolas; Bonzon, Lucas
- Abstract
This article discusses a case report of a patient who developed a disseminated invasive infection caused by Corynebacterium simulans, a type of bacteria commonly found on the skin and in the mouth. The patient was initially treated with daptomycin, an antibiotic with broad activity against Gram-positive bacteria, but quickly developed high-level resistance to the drug. The authors recommend caution when using daptomycin as monotherapy for invasive Corynebacterium infections and suggest using glycopeptides or a combination of glycopeptides and oral drugs like linezolid instead. The study highlights the need for further research and treatment guidelines for infections caused by this bacterial genus.
- Subjects
DAPTOMYCIN; CORYNEBACTERIUM; PROSTHESIS-related infections; HERBICIDE resistance
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2024, Vol 79, Issue 3, p687
- ISSN
0305-7453
- Publication type
Article
- DOI
10.1093/jac/dkad409