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- Title
VARIAÇÕES PLASMÁTICAS DE AMINAS VASOATIVAS EM EQUINOS SOB EFEITO DE SOBRECARGA DE CARBOIDRATOS E ANTI-INFLAMATÓRIOS NÃO ESTEROIDAIS.
- Authors
Costa, Renata Sampaio; De Tarso Landgraf Botteon, Paulo; Ferraz, Vany Perpétua; De Oliveira Paes Leme, Fabíola; Faleiros, Rafael Resende; Alves, Geraldo Eleno Silveira
- Abstract
Twenty horses were submitted to carbohydrate overload (CO) and plasmatic concentrations of the bioactive amine serotonin (5-HT), putrescin (PUT) and cadaverin (CAD) were determined by gas chromatography. After 36h of carbohydrate overloading, horses were randomly distributed into four groups (n=5) and were submitted to four intravenous treatments every 12 hours. The treatments were as follows: 10ml of saline (GC), ketoprofen 2.2mg/kg (GK), phenylbutazone 4.4mg/kg (GF), and flunixin meglumine 1.1mg/kg (GFM). Blood samples were collected at regular intervals (0-72h) after the CO. After 6h, there were peaks in the concentrations of 5-HT, which rapidly returned to values above the basal standard. No variations of PUT concentrations were observed; however CAD concentrations increased at 6h, remaining elevated (with some variation) until the end of the observation period. In conclusion, CO induced early (6h) increases in plasmatic concentrations of 5-HT and CAD. Plasmatic concentrations of the amines were not changed by any of the treatments used.
- Subjects
HORSES; CARBOHYDRATES in animal nutrition; AMINES; ANIMAL nutrition; ANTI-inflammatory agents; SEROTONIN; PUTRESCINE
- Publication
Ciência Animal Brasileira, 2012, Vol 13, Issue 1, p93
- ISSN
1518-2797
- Publication type
Article
- DOI
10.5216/cab.v13i1.6970