OpenURL Connection Search

Select item for more details and to access through your institution.

Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria.
Published in:
International Journal of Molecular Sciences, 2015, v. 16, n. 7, p. 15287, doi. 10.3390/ijms160715287
By:
- Daniel Ken Inaoka;
- Tomoo Shiba;
- Dan Sato;
- Balogun, Emmanuel Oluwadare;
- Tsuyoshi Sasaki;
- Madoka Nagahama;
- Masatsugu Oda;
- Shigeru Matsuoka;
- Junko Ohmori;
- Teruki Honma;
- Masayuki Inoue;
- Kiyoshi Kita;
- Shigeharu Harada
Publication type:
Article
N‐(3,4‐dimethoxyphenethyl)‐6‐methyl‐2,3,4,9‐tetrahydro‐1H‐carbazol‐1‐amine inhibits bladder cancer progression by suppressing YAP1/TAZ.
Published in:
Genes to Cells, 2022, v. 27, n. 10, p. 602, doi. 10.1111/gtc.12979
By:
- Shiraishi, Yusuke;
- Maehama, Tomohiko;
- Nishio, Miki;
- Otani, Junji;
- Hikasa, Hiroki;
- Mak, Tak Wah;
- Sasaki, Takehiko;
- Honma, Teruki;
- Kondoh, Yasumitsu;
- Osada, Hiroyuki;
- Yoshida, Minoru;
- Fujisawa, Masato;
- Suzuki, Akira
Publication type:
Article
Pharmacophore Modeling for Anti-Chagas Drug Design Using the Fragment Molecular Orbital Method.
Published in:
PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125829
By:
- Yoshino, Ryunosuke;
- Yasuo, Nobuaki;
- Inaoka, Daniel Ken;
- Hagiwara, Yohsuke;
- Ohno, Kazuki;
- Orita, Masaya;
- Inoue, Masayuki;
- Shiba, Tomoo;
- Harada, Shigeharu;
- Honma, Teruki;
- Balogun, Emmanuel Oluwadare;
- da Rocha, Josmar Rodrigues;
- Montanari, Carlos Alberto;
- Kita, Kiyoshi;
- Sekijima, Masakazu
Publication type:
Article
Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
Published in:
Molecular Microbiology, 2014, v. 94, n. 6, p. 1315, doi. 10.1111/mmi.12831
By:
- Balogun, Emmanuel Oluwadare;
- Inaoka, Daniel Ken;
- Shiba, Tomoo;
- Kido, Yasutoshi;
- Tsuge, Chiaki;
- Nara, Takeshi;
- Aoki, Takashi;
- Honma, Teruki;
- Tanaka, Akiko;
- Inoue, Masayuki;
- Matsuoka, Shigeru;
- Michels, Paul A. M.;
- Kita, Kiyoshi;
- Harada, Shigeharu
Publication type:
Article
The ubiquinone synthesis pathway is a promising drug target for Chagas disease.
Published in:
PLoS ONE, 2021, v. 16, n. 2, p. 1, doi. 10.1371/journal.pone.0243855
By:
- Nara, Takeshi;
- Nakagawa, Yukari;
- Tsuganezawa, Keiko;
- Yuki, Hitomi;
- Sekimata, Katsuhiko;
- Koyama, Hiroo;
- Ogawa, Naoko;
- Honma, Teruki;
- Shirouzu, Mikako;
- Fukami, Takehiro;
- Matsuo, Yuichi;
- Inaoka, Daniel Ken;
- Kita, Kiyoshi;
- Tanaka, Akiko
Publication type:
Article
Support Vector Machine model for hERG inhibitory activities based on the integrated hERG database using descriptor selection by NSGA-II.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47536-3
By:
- Ogura, Keiji;
- Sato, Tomohiro;
- Yuki, Hitomi;
- Honma, Teruki
Publication type:
Article
kGCN: a graph-based deep learning framework for chemical structures.
Published in:
Journal of Cheminformatics, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13321-020-00435-6
By:
- Kojima, Ryosuke;
- Ishida, Shoichi;
- Ohta, Masateru;
- Iwata, Hiroaki;
- Honma, Teruki;
- Okuno, Yasushi
Publication type:
Article
Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase.
Published in:
PLoS Neglected Tropical Diseases, 2019, v. 13, n. 11, p. 1, doi. 10.1371/journal.pntd.0007894
By:
- Shimizu, Hideaki;
- Saito, Akatsuki;
- Mikuni, Junko;
- Nakayama, Emi E.;
- Koyama, Hiroo;
- Honma, Teruki;
- Shirouzu, Mikako;
- Sekine, Shun-ichi;
- Shioda, Tatsuo
Publication type:
Article
Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.
Published in:
FASEB Journal, 2019, v. 33, n. 11, p. 13002, doi. 10.1096/fj.201901342R
By:
- Balogun, Emmanuel Oluwadare;
- Inaoka, Daniel Ken;
- Tomoo Shiba;
- Chiaki Tsuge;
- May, Benjamin;
- Tomohiro Sato;
- Yasutoshi Kido;
- Takeshi Nara;
- Takashi Aoki;
- Teruki Honma;
- Akiko Tanaka;
- Masayuki Inoue;
- Shigeru Matsuoka;
- Michels, Paul A. M.;
- Yoh-Ichi Watanabe;
- Moore, Anthony L.;
- Shigeharu Harada;
- Kiyoshi Kita
Publication type:
Article
Recent advances in de novo design strategy for practical lead identification.
Published in:
Medicinal Research Reviews, 2003, v. 23, n. 5, p. 606, doi. 10.1002/med.10046
By:
- Teruki Honma
Publication type:
Article
Biochemical characterization of highly active Trypanosoma brucei gambiense glycerol kinase, a promising drug target.
Published in:
Journal of Biochemistry, 2013, v. 154, n. 1, p. 77, doi. 10.1093/jb/mvt037
By:
- Balogun, Emmanuel Oluwadare;
- Inaoka, Daniel Ken;
- Shiba, Tomoo;
- Kido, Yasutoshi;
- Nara, Takeshi;
- Aoki, Takashi;
- Honma, Teruki;
- Tanaka, Akiko;
- Inoue, Masayuki;
- Matsuoka, Shigeru;
- Michels, Paul AM.;
- Harada, Shigeharu;
- Kita, Kiyoshi
Publication type:
Article
Protein–ligand binding affinity prediction of cyclin‐dependent kinase‐2 inhibitors by dynamically averaged fragment molecular orbital‐based interaction energy.
Published in:
Journal of Computational Chemistry, 2022, v. 43, n. 20, p. 1362, doi. 10.1002/jcc.26940
By:
- Takaba, Kenichiro;
- Watanabe, Chiduru;
- Tokuhisa, Atsushi;
- Akinaga, Yoshinobu;
- Ma, Biao;
- Kanada, Ryo;
- Araki, Mitsugu;
- Okuno, Yasushi;
- Kawashima, Yusuke;
- Moriwaki, Hirotomo;
- Kawashita, Norihito;
- Honma, Teruki;
- Fukuzawa, Kaori;
- Tanaka, Shigenori
Publication type:
Article
A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo.
Published in:
Science Translational Medicine, 2013, v. 5, n. 181, p. 1, doi. 10.1126/scitranslmed.3004387
By:
- Yoriko Saito;
- Hitomi Yuki;
- Mitsuo Kuratani;
- Yoshinobu Hashizume;
- Shinsuke Takagi;
- Teruki Honma;
- Akiko Tanaka;
- Mikako Shirouzu;
- Junko Mikuni;
- Noriko Handa;
- Ikuko Ogahara;
- Akiko Sone;
- Yuho Najima;
- Yuri Tomabechi;
- Motoaki Wakiyama;
- Naoyuki Uchida;
- Mariko Tomizawa-Murasawa;
- Akiko Kaneko;
- Satoshi Tanaka;
- Nahoko Suzuki
Publication type:
Article
The Open Form Inducer Approach for Structure-Based Drug Design.
Published in:
PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167078
By:
- Inaoka, Daniel Ken;
- Iida, Maiko;
- Tabuchi, Toshiyuki;
- Honma, Teruki;
- Lee, Nayoung;
- Hashimoto, Satoshi;
- Matsuoka, Shigeru;
- Kuranaga, Takefumi;
- Sato, Kazuhito;
- Shiba, Tomoo;
- Sakamoto, Kimitoshi;
- Balogun, Emmanuel Oluwadare;
- Suzuki, Shigeo;
- Nara, Takeshi;
- Rocha, Josmar Rodrigues da;
- Montanari, Carlos Alberto;
- Tanaka, Akiko;
- Inoue, Masayuki;
- Kita, Kiyoshi;
- Harada, Shigeharu
Publication type:
Article
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.
Published in:
Nature, 2013, v. 503, n. 7477, p. 493, doi. 10.1038/nature12656
By:
- Okada-Iwabu, Miki;
- Yamauchi, Toshimasa;
- Iwabu, Masato;
- Honma, Teruki;
- Hamagami, Ken-ichi;
- Matsuda, Koichi;
- Yamaguchi, Mamiko;
- Tanabe, Hiroaki;
- Kimura-Someya, Tomomi;
- Shirouzu, Mikako;
- Ogata, Hitomi;
- Tokuyama, Kumpei;
- Ueki, Kohjiro;
- Nagano, Tetsuo;
- Tanaka, Akiko;
- Yokoyama, Shigeyuki;
- Kadowaki, Takashi
Publication type:
Article
Structural basis of transcription regulation by CNC family transcription factor, Nrf2.
Published in:
Nucleic Acids Research, 2022, v. 50, n. 21, p. 12543, doi. 10.1093/nar/gkac1102
By:
- Sengoku, Toru;
- Shiina, Masaaki;
- Suzuki, Kae;
- Hamada, Keisuke;
- Sato, Ko;
- Uchiyama, Akiko;
- Kobayashi, Shunsuke;
- Oguni, Asako;
- Itaya, Hayato;
- Kasahara, Kota;
- Moriwaki, Hirotomo;
- Watanabe, Chiduru;
- Honma, Teruki;
- Okada, Chikako;
- Baba, Shiho;
- Ohta, Tsutomu;
- Motohashi, Hozumi;
- Yamamoto, Masayuki;
- Ogata, Kazuhiro
Publication type:
Article
AI-driven molecular generation of not-patented pharmaceutical compounds using world open patent data.
Published in:
Journal of Cheminformatics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13321-023-00791-z
By:
- Shimizu, Yugo;
- Ohta, Masateru;
- Ishida, Shoichi;
- Terayama, Kei;
- Osawa, Masanori;
- Honma, Teruki;
- Ikeda, Kazuyoshi
Publication type:
Article
Construction of an integrated database for hERG blocking small molecules.
Published in:
PLoS ONE, 2018, p. 1, doi. 10.1371/journal.pone.0199348
By:
- Sato, Tomohiro;
- Yuki, Hitomi;
- Ogura, Keiji;
- Honma, Teruki
Publication type:
Article
Alantolactone is a natural product that potently inhibits YAP1/TAZ through promotion of reactive oxygen species accumulation.
Published in:
Cancer Science, 2021, v. 112, n. 10, p. 4303, doi. 10.1111/cas.15079
By:
- Nakatani, Keisuke;
- Maehama, Tomohiko;
- Nishio, Miki;
- Otani, Junji;
- Yamaguchi, Keiko;
- Fukumoto, Miki;
- Hikasa, Hiroki;
- Hagiwara, Shinji;
- Nishina, Hiroshi;
- Mak, Tak Wah;
- Honma, Teruki;
- Kondoh, Yasumitsu;
- Osada, Hiroyuki;
- Yoshida, Minoru;
- Suzuki, Akira
Publication type:
Article
Force‐field parametrization based on radial and energy distribution functions.
Published in:
Journal of Computational Chemistry, 2019, v. 40, n. 29, p. 2577, doi. 10.1002/jcc.26035
By:
- Chiba, Shuntaro;
- Okuno, Yasushi;
- Honma, Teruki;
- Ikeguchi, Mitsunori
Publication type:
Article

Found: 20