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Proteomic characterisation of triple negative breast cancer cells following CDK4/6 inhibition.
Published in:
Scientific Data, 2022, v. 9, n. 1, p. 1, doi. 10.1038/s41597-022-01512-1
By:
- Beykou, Melina;
- Arias-Garcia, Mar;
- Roumeliotis, Theodoros I.;
- Choudhary, Jyoti S.;
- Moser, Nicolas;
- Georgiou, Pantelis;
- Bakal, Chris
Publication type:
Article
Citrobacter rodentium induces rapid and unique metabolic and inflammatory responses in mice suffering from severe disease.
Published in:
Cellular Microbiology, 2020, v. 22, n. 1, p. N.PAG, doi. 10.1111/cmi.13126
By:
- Carson, Danielle;
- Barry, Rachael;
- Hopkins, Eve G.D.;
- Roumeliotis, Theodoros I.;
- García‐Weber, Diego;
- Mullineaux‐Sanders, Caroline;
- Elinav, Eran;
- Arrieumerlou, Cécile;
- Choudhary, Jyoti S.;
- Frankel, Gad
Publication type:
Article
Author Correction: Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling.
Published in:
2023
By:
- Koliopoulos, Marios G.;
- Muhammad, Reyhan;
- Roumeliotis, Theodoros I.;
- Beuron, Fabienne;
- Choudhary, Jyoti S.;
- Alfieri, Claudio
Publication type:
Correction Notice
HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35143-2
By:
- Oberoi, Jasmeen;
- Guiu, Xavi Aran;
- Outwin, Emily A.;
- Schellenberger, Pascale;
- Roumeliotis, Theodoros I.;
- Choudhary, Jyoti S.;
- Pearl, Laurence H.
Publication type:
Article
Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32798-9
By:
- Koliopoulos, Marios G.;
- Muhammad, Reyhan;
- Roumeliotis, Theodoros I.;
- Beuron, Fabienne;
- Choudhary, Jyoti S.;
- Alfieri, Claudio
Publication type:
Article
Aneuploidy tolerance caused by BRG1 loss allows chromosome gains and recovery of fitness.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29420-3
By:
- Schiavoni, Federica;
- Zuazua-Villar, Pedro;
- Roumeliotis, Theodoros I.;
- Benstead-Hume, Graeme;
- Pardo, Mercedes;
- Pearl, Frances M. G.;
- Choudhary, Jyoti S.;
- Downs, Jessica A.
Publication type:
Article
Spatial control of the APC/C ensures the rapid degradation of cyclin B1.
Published in:
EMBO Journal, 2024, v. 43, n. 19, p. 4324, doi. 10.1038/s44318-024-00194-2
By:
- Cirillo, Luca;
- Young, Rose;
- Veerapathiran, Sapthaswaran;
- Roberti, Annalisa;
- Martin, Molly;
- Abubacar, Azzah;
- Perosa, Camilla;
- Coates, Catherine;
- Muhammad, Reyhan;
- Roumeliotis, Theodoros I;
- Choudhary, Jyoti S;
- Alfieri, Claudio;
- Pines, Jonathon
Publication type:
Article
Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46392-8
By:
- Mazza, Tiziano;
- Roumeliotis, Theodoros I.;
- Garitta, Elena;
- Drew, David;
- Rashid, S. Tamir;
- Indiveri, Cesare;
- Choudhary, Jyoti S.;
- Linton, Kenneth J.;
- Beis, Konstantinos
Publication type:
Article
The proteomic landscape of soft tissue sarcomas.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39486-2
By:
- Burns, Jessica;
- Wilding, Christopher P.;
- Krasny, Lukas;
- Zhu, Xixuan;
- Chadha, Madhumeeta;
- Tam, Yuen Bun;
- PS, Hari;
- Mahalingam, Aswanth H.;
- Lee, Alexander T. J.;
- Arthur, Amani;
- Guljar, Nafia;
- Perkins, Emma;
- Pankova, Valeriya;
- Jenks, Andrew;
- Djabatey, Vanessa;
- Szecsei, Cornelia;
- McCarthy, Frank;
- Ragulan, Chanthirika;
- Milighetti, Martina;
- Roumeliotis, Theodoros I.
Publication type:
Article
Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38276-0
By:
- Wan, Mandy S. M.;
- Muhammad, Reyhan;
- Koliopoulos, Marios G.;
- Roumeliotis, Theodoros I.;
- Choudhary, Jyoti S.;
- Alfieri, Claudio
Publication type:
Article
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08886-8
By:
- Bianco, Julien N.;
- Bergoglio, Valérie;
- Lin, Yea-Lih;
- Pillaire, Marie-Jeanne;
- Schmitz, Anne-Lyne;
- Gilhodes, Julia;
- Lusque, Amelie;
- Mazières, Julien;
- Lacroix-Triki, Magali;
- Roumeliotis, Theodoros I.;
- Choudhary, Jyoti;
- Moreaux, Jérôme;
- Hoffmann, Jean-Sébastien;
- Tourrière, Hélène;
- Pasero, Philippe
Publication type:
Article
An E2-ubiquitin thioester-driven approach to identify substrates modified with ubiquitin and ubiquitin-like molecules.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07251-5
By:
- Bakos, Gábor;
- Yu, Lu;
- Gak, Igor A.;
- Roumeliotis, Theodoros I.;
- Liakopoulos, Dimitris;
- Choudhary, Jyoti S.;
- Mansfeld, Jörg
Publication type:
Article
Increased circulating resistin levels in early-onset breast cancer patients of normal body mass index correlate with lymph node negative involvement and longer disease free survival: a multi-center POSH cohort serum proteomics study.
Published in:
2018
By:
- Zeidan, Bashar;
- Manousopoulou, Antigoni;
- Garay-Baquero, Diana J.;
- White, Cory H.;
- Larkin, Samantha E. T.;
- Potter, Kathleen N.;
- Roumeliotis, Theodoros I.;
- Papachristou, Evangelia K.;
- Copson, Ellen;
- Cutress, Ramsey I.;
- Beers, Stephen A.;
- Eccles, Diana;
- Townsend, Paul A.;
- Garbis, Spiros D.
Publication type:
journal article
Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.
Published in:
Molecular Oncology, 2024, v. 18, n. 2, p. 369, doi. 10.1002/1878-0261.13537
By:
- Baxter, Joseph S.;
- Brough, Rachel;
- Krastev, Dragomir B.;
- Song, Feifei;
- Sridhar, Sandhya;
- Gulati, Aditi;
- Alexander, John;
- Roumeliotis, Theodoros I.;
- Kozik, Zuza;
- Choudhary, Jyoti S.;
- Haider, Syed;
- Pettitt, Stephen J.;
- Tutt, Andrew N. J.;
- Lord, Christopher J.
Publication type:
Article
Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 20, p. 6838, doi. 10.1523/JNEUROSCI.5699-09.2010
By:
- Emmanouilidou, Evangelia;
- Melachroinou, Katerina;
- Roumeliotis, Theodoros;
- Garbis, Spiros D.;
- Ntzouni, Maria;
- Margaritis, Lukas H.;
- Stefanis, Leonidas;
- Vekrellis, Kostas
Publication type:
Article
The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses.
Published in:
PLoS Pathogens, 2018, v. 14, n. 10, p. 1, doi. 10.1371/journal.ppat.1007406
By:
- Berger, Cedric N.;
- Crepin, Valerie F.;
- Roumeliotis, Theodoros I.;
- Wright, James C.;
- Serafini, Nicolas;
- Pevsner-Fischer, Meirav;
- Yu, Lu;
- Elinav, Eran;
- Di Santo, James P.;
- Choudhary, Jyoti S.;
- Frankel, Gad
Publication type:
Article
Front Cover: A Degron Blocking Strategy Towards Improved CRL4<sup>CRBN</sup> Recruiting PROTAC Selectivity (ChemBioChem 23/2023).
Published in:
ChemBioChem, 2023, v. 24, n. 23, p. 1, doi. 10.1002/cbic.202300692
By:
- Bouguenina, Habib;
- Scarpino, Andrea;
- O'Hanlon, Jack A.;
- Warne, Justin;
- Wang, Hannah Z.;
- Wah Hak, Laura Chan;
- Sadok, Amine;
- McAndrew, P. Craig;
- Stubbs, Mark;
- Pierrat, Olivier A.;
- Hahner, Tamas;
- Cabry, Marc P.;
- Le Bihan, Yann‐Vaï;
- Mitsopoulos, Costas;
- Sialana, Fernando J.;
- Roumeliotis, Theodoros I.;
- Burke, Rosemary;
- van Montfort, Rob L. M.;
- Choudhari, Jyoti;
- Chopra, Rajesh
Publication type:
Article
A Degron Blocking Strategy Towards Improved CRL4<sup>CRBN</sup> Recruiting PROTAC Selectivity.
Published in:
ChemBioChem, 2023, v. 24, n. 23, p. 1, doi. 10.1002/cbic.202300351
By:
- Bouguenina, Habib;
- Scarpino, Andrea;
- O'Hanlon, Jack A.;
- Warne, Justin;
- Wang, Hannah Z.;
- Wah Hak, Laura Chan;
- Sadok, Amine;
- McAndrew, P. Craig;
- Stubbs, Mark;
- Pierrat, Olivier A.;
- Hahner, Tamas;
- Cabry, Marc P.;
- Le Bihan, Yann‐Vaï;
- Mitsopoulos, Costas;
- Sialana, Fernando J.;
- Roumeliotis, Theodoros I.;
- Burke, Rosemary;
- van Montfort, Rob L. M.;
- Choudhari, Jyoti;
- Chopra, Rajesh
Publication type:
Article
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.
Published in:
Nature Cell Biology, 2013, v. 15, n. 10, p. 1260, doi. 10.1038/ncb2852
By:
- Velimezi, Georgia;
- Liontos, Michalis;
- Vougas, Konstantinos;
- Roumeliotis, Theodoros;
- Bartkova, Jirina;
- Sideridou, Maria;
- Dereli-Oz, Ayguel;
- Kocylowski, Maciej;
- Pateras, Ioannis S.;
- Evangelou, Kostas;
- Kotsinas, Athanassios;
- Orsolic, Ines;
- Bursac, Sladana;
- Cokaric-Brdovcak, Maja;
- Zoumpourlis, Vassilis;
- Kletsas, Dimitris;
- Papafotiou, George;
- Klinakis, Apostolos;
- Volarevic, Sinisa;
- Gu, Wei
Publication type:
Article
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.
Published in:
Nature Cell Biology, 2013, v. 15, n. 8, p. 967, doi. 10.1038/ncb2795
By:
- Velimezi, Georgia;
- Liontos, Michalis;
- Vougas, Konstantinos;
- Roumeliotis, Theodoros;
- Bartkova, Jirina;
- Sideridou, Maria;
- Dereli-Oz, Ayguel;
- Kocylowski, Maciej;
- Pateras, Ioannis S.;
- Evangelou, Kostas;
- Kotsinas, Athanassios;
- Orsolic, Ines;
- Bursac, Sladana;
- Cokaric-Brdovcak, Maja;
- Zoumpourlis, Vassilis;
- Kletsas, Dimitris;
- Papafotiou, George;
- Klinakis, Apostolos;
- Volarevic, Sinisa;
- Gu, Wei
Publication type:
Article
Resistance of naturally secreted α-synuclein to proteolysis.
Published in:
FASEB Journal, 2014, v. 28, n. 7, p. 3146, doi. 10.1096/fj.13-245852
By:
- Ximerakis, Methodios;
- Pampalakis, Georgios;
- Roumeliotis, Theodoros I.;
- Sykioti, Vasia-Samantha;
- Garbis, Spiros D.;
- Stefanis, Leonidas;
- Sotiropoulou, Georgia;
- Vekrellis, Kostas
Publication type:
Article
Muscle lim protein isoform negatively regulates striated muscle actin dynamics and differentiation.
Published in:
FEBS Journal, 2014, v. 281, n. 14, p. 3261, doi. 10.1111/febs.12859
By:
- Vafiadaki, Elizabeth;
- Arvanitis, Demetrios A.;
- Papalouka, Vasiliki;
- Terzis, Gerasimos;
- Roumeliotis, Theodoros I.;
- Spengos, Konstantinos;
- Garbis, Spiros D.;
- Manta, Panagiota;
- Kranias, Evangelia G.;
- Sanoudou, Despina
Publication type:
Article
Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx–dependent pyroptosis in intestinal epithelial cells.
Published in:
PLoS Biology, 2020, v. 18, n. 12, p. 1, doi. 10.1371/journal.pbio.3000986
By:
- Zhong, Qiyun;
- Roumeliotis, Theodoros I.;
- Kozik, Zuza;
- Cepeda-Molero, Massiel;
- Fernández, Luis Ángel;
- Shenoy, Avinash R.;
- Bakal, Chris;
- Frankel, Gad;
- Choudhary, Jyoti S.
Publication type:
Article
Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis.
Published in:
Rheumatology, 2018, v. 57, n. 8, p. 1481, doi. 10.1093/rheumatology/key101
By:
- Steinberg, Julia;
- Brooks, Roger A;
- Southam, Lorraine;
- Bhatnagar, Sahir;
- Roumeliotis, Theodoros I;
- Hatzikotoulas, Konstantinos;
- Zengini, Eleni;
- Wilkinson, J Mark;
- Choudhary, Jyoti S;
- McCaskie, Andrew W
Publication type:
Article
Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis.
Published in:
Nature Communications, 2017, v. 8, n. 4, p. 15013, doi. 10.1038/ncomms15013
By:
- Yeung, Amy T. Y.;
- Hale, Christine;
- Lee, Amy H.;
- Gill, Erin E.;
- Bushell, Wendy;
- Parry-Smith, David;
- Goulding, David;
- Pickard, Derek;
- Roumeliotis, Theodoros;
- Choudhary, Jyoti;
- Thomson, Nick;
- Skarnes, William C.;
- Dougan, Gordon;
- Hancock, Robert E. W.
Publication type:
Article
A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatinassociated protein complexes.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04619-5
By:
- Papachristou, Evangelia K.;
- Kishore, Kamal;
- Holding, Andrew N.;
- Harvey, Kate;
- Roumeliotis, Theodoros I.;
- Chilamakuri, Chandra Sekhar Reddy;
- Omarjee, Soleilmane;
- Kee Ming Chia;
- Swarbrick, Alex;
- Elgene Lim;
- Markowetz, Florian;
- Eldridge, Matthew;
- Siersbaek, Rasmus;
- D’Santos, Clive S.;
- Carroll, Jason S.
Publication type:
Article
m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49139-7
By:
- Klein, Pierre;
- Petrić Howe, Marija;
- Harley, Jasmine;
- Crook, Harry;
- Esteban Serna, Sofia;
- Roumeliotis, Theodoros I.;
- Choudhary, Jyoti S.;
- Chakrabarti, Anob M.;
- Luisier, Raphaëlle;
- Patani, Rickie;
- Ramos, Andres
Publication type:
Article
A molecular quantitative trait locus map for osteoarthritis.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21593-7
By:
- Steinberg, Julia;
- Southam, Lorraine;
- Roumeliotis, Theodoros I.;
- Clark, Matthew J.;
- Jayasuriya, Raveen L.;
- Swift, Diane;
- Shah, Karan M.;
- Butterfield, Natalie C.;
- Brooks, Roger A.;
- McCaskie, Andrew W.;
- Bassett, J. H. Duncan;
- Williams, Graham R.;
- Choudhary, Jyoti S.;
- Wilkinson, J. Mark;
- Zeggini, Eleftheria
Publication type:
Article
Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15543-y
By:
- Cano-Gamez, Eddie;
- Soskic, Blagoje;
- Roumeliotis, Theodoros I.;
- So, Ernest;
- Smyth, Deborah J.;
- Baldrighi, Marta;
- Willé, David;
- Nakic, Nikolina;
- Esparza-Gordillo, Jorge;
- Larminie, Christopher G. C.;
- Bronson, Paola G.;
- Tough, David F.;
- Rowan, Wendy C.;
- Choudhary, Jyoti S.;
- Trynka, Gosia
Publication type:
Article

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