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- Title
Regioselective Oxidative Homocoupling Reaction: An Efficient Copper-Catalyzed Synthesis of Biimidazo[1,2- a]pyridines.
- Authors
Lei, Sai; Cao, Hua; Chen, Longbin; Liu, Jingyun; Cai, Huiyin; Tan, Jingwen
- Abstract
A facile and efficient copper(I)-catalyzed intermolecular direct CH homocoupling of imidazo[1,2- a]pyridines with excellent C-3 regioselectivity in dimethyl sulfoxide (DMSO) has been developed. This transformation provides a straightforward and operationally simple route for the preparation of biimidazo[1,2- a]pyridines which are an important structural motif in natural products and pharmaceuticals.
- Subjects
COUPLING reactions (Chemistry); PYRIDINE synthesis; COPPER catalysts; REGIOSELECTIVITY (Chemistry); DIMETHYL sulfoxide
- Publication
Advanced Synthesis & Catalysis, 2015, Vol 357, Issue 14/15, p3109
- ISSN
1615-4150
- Publication type
Article
- DOI
10.1002/adsc.201500391