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- Title
Comparison of Effects of Verapamil and Quercetin on Delayed Polyneuropathy Induced by Tri-o-Cresyl Phosphate in Hens.
- Authors
Wu, Y.-J.; Leng, X.-F.
- Abstract
The article presents a study which evaluates the effects the effects of verapamil and quercetin on delayed polyneuropathy induced by Tri-o-Cresyl phosphate in hens. The study has suggested that the increase of intracellular calcium concentration may be involved in the mechanism of development of organosphosphate-induced delayed polyneuropathy (OPIDP). OPIDP is characterized by pathological lesions in peripheral axons 7-14 days before onset of clinical pathologies. Calcium channel blockers have been found to ameliorate the clinical response to phenyl saligenin phosphate.
- Subjects
VERAPAMIL; QUERCETIN; PHOSPHATES; HENS; CALCIUM antagonists; AXONS; CALCIUM channels; POLYNEUROPATHIES; PATHOLOGY
- Publication
Bulletin of Environmental Contamination & Toxicology, 1997, Vol 58, Issue 4, p611
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/s001289900378