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- Title
The effect of 1% chlorhexidine gel and 0.12% dentifrice gel on plaque accumulation: a 3-day non-brushing model.
- Authors
Slot, D. E.; Rosema, N. A. M.; Hennequin-Hoenderdos, N. L.; Versteeg, P. A.; van der Velden, U.; van der Weijden, G. A.
- Abstract
To cite this article: Int J Dent Hygiene 8, 2010; 294-300 DOI: 10.1111/j.1601-5037.2010.00487.x Slot DE, Rosema NAM, Hennequin-Hoenderdos NL, Versteeg PA, van der Velden U, van der Weijden GA. The effect of 1% chlorhexidine gel and 0.12% dentifrice gel on plaque accumulation: a 3-day non-brushing model. Aim: The purpose of the study was to compare the effects of four treatments on 'de novo' plaque accumulation. Treatments included tray application of 1% chlorhexidine gel (CHX-Gel), 0.12% chlorhexidine dentifrice-gel (CHX-DFG), a regular dentifrice (RDF) tray application, or 0.2% chlorhexidine mouthwash (CHX-MW) in a 3-day non-brushing model. Material and methods: The study was designed as a single blind, randomized parallel clinical trial. After professional prophylaxis, subjects abstained from all other forms of oral hygiene during a 3-day non-brushing period. Subjects were randomly assigned to one of the four test groups (CHX-Gel, CHX-DFG, RDF applied in a fluoride gel tray or rinsing with a CHX-MW). After 3 days, the Quigley & Hein plaque index (PI) and Bleeding on Marginal Probing (BOMP) index was assessed. Subsequently, all subjects received a questionnaire to evaluate their attitude, appreciation and perception towards the products used employing a Visual Analogue Scale. Results: After 3 days, the full-mouth PI means were 0.88 for the CHX-gel regimen, 0.79 for CHX-MW, 1.16 for CHX-DFG and 1.31 for the RDF regimen. The two dentifrices (CHX-DFG and RDF) were significantly less effective than the CHX-Gel or the CHX-MW. Conclusion: Within the limitations of the present 3-day non-brushing study design, it can be concluded that the effect of a 1% CHX-Gel application tray is significantly greater than that of 0.12% CHX-DFG or RDF in inhibiting plaque accumulation. The 1% CHX-Gel applied via a tray and 0.2% CHX-MW rinse were comparably effective.
- Subjects
NETHERLANDS; DENTAL plaque; DENTIFRICES; CHLORHEXIDINE; ANALYSIS of variance; COMPARATIVE studies; CONFIDENCE intervals; LONGITUDINAL method; MOUTHWASHES; NURSING assessment; QUESTIONNAIRES; STATISTICAL sampling; SCALE analysis (Psychology); T-test (Statistics); EMAIL; SAMPLE size (Statistics); STATISTICAL significance; HUMAN research subjects; BLIND experiment; PATIENT selection; DRUG administration; DRUG dosage; THERAPEUTICS; PREVENTION
- Publication
International Journal of Dental Hygiene, 2010, Vol 8, Issue 4, p294
- ISSN
1601-5029
- Publication type
Article
- DOI
10.1111/j.1601-5037.2010.00487.x