We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Advances in gut microbiota in the pathogenesis and treatment of inflammatory bowel disease.
- Authors
LI Bowen; LIU Ningning; WANG Hui
- Abstract
The gut microbiota plays a critical role in human health. Inflammatory bowel disease (IBD) is an immunological disease caused by various environmental factors, including the gut microbiota, in genetically susceptible individuals. Although most studies have indicated the role of gut microbiota and their metabolites in contribution to the occurrence and development of intestinal diseases by inducing inflammation and immune disorders. However, the causal relationship between microbiota and IBD pathogenesis cannot be determined. In this review, the alteration of bacterial, fungal and viral microbiota and the potential functional pathways during IBD pathogenesis are summarized. Besides, the current therapeutic approaches targeting microbiota and the promising perspectives are introduced.
- Publication
Journal of Shanghai Jiaotong University (Medical Science), 2022, Vol 42, Issue 3, p364
- ISSN
1674-8115
- Publication type
Article
- DOI
10.3969/j.issn.1674-8115.2022.03.015