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- Title
Allergic contact dermatitis from a skin‐calming cream containing hydroxyphenyl propamidobenzoic acid.
- Authors
Blanchard, Gabriela; Walker, Anna; Dendooven, Ella; Aerts, Olivier; Goossens, An; Gilliet, Michel; Seremet, Teofila
- Abstract
Allergic contact dermatitis from a skin-calming cream containing hydroxyphenyl propamidobenzoic acid Keywords: allergic contact dermatitis; CAS 697235-49-7; case report; cosmetics; dihydroavenanthramide D; glycols; hydroxyphenyl propamidobenzoic acid; medical device; patch testing; Symcalmin EN allergic contact dermatitis CAS 697235-49-7 case report cosmetics dihydroavenanthramide D glycols hydroxyphenyl propamidobenzoic acid medical device patch testing Symcalmin 68 70 3 12/21/22 20230101 NES 230101 Hydroxyphenyl propamidobenzoic acid (HPPBA; syn. dihydroavenanthramide D) is a synthetic analogue of naturally occurring avenanthramide which can be found in oats.[1] Symcalmin is a 5% solution of HPPBA in a vehicle of (1:1) butylene glycol and pentylene glycol and is commonly used by the pharmaceutical and cosmetic industry for its anti-inflammatory and anti-oxidant (i.e., anti-irritant and anti-itch) properties.[[2], [4]] We report the first case of allergic contact dermatitis (ACD) likely caused by HPPBA. Allergic contact dermatitis, CAS 697235-49-7, case report, cosmetics, dihydroavenanthramide D, glycols, hydroxyphenyl propamidobenzoic acid, medical device, patch testing, Symcalmin.
- Subjects
CONTACT dermatitis; ECZEMA; DE Quervain disease; HYDROXYCINNAMIC acids
- Publication
Contact Dermatitis (01051873), 2023, Vol 88, Issue 1, p68
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/cod.14221