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- Title
Response to: Patch test reactivity to aluminium chambers.
- Authors
Inerot, Annica; Bergfors, Elisabet; Trollfors, Birger
- Abstract
During the 1990s, a mass vaccination study of a new acellular pertussis vaccine adsorbed onto aluminum hydroxide was performed in the Gothenburg area of Sweden.[1] Among about 76 000 vaccinated children, 645 children developed itching nodules at the site of injection. Most siblings (n = 211) had received the same acellular vaccine and to our surprise 8% of these siblings were also positive to the aluminum patch test.[2] The remaining asymptomatic siblings (n = 54) were all negative and none of these had received the aluminum hydroxide vaccine but instead they had been exposed to aluminum phosphate in the diphtheria-tetanus vaccine in infancy. 2 Bergfors E, Trollfors B, Inerot A. Unexpectedly high incidence of persistent itching nodules and delayed hypersensitivity to aluminium in children after the use of adsorbed vaccines from a single manufacturer.
- Subjects
ALUMINUM; WHOOPING cough vaccines; VACCINATION of children; ALUMINUM phosphate; DELAYED hypersensitivity
- Publication
Contact Dermatitis (01051873), 2020, Vol 82, Issue 2, p135
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/cod.13433