We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Is implantable cardioverter defibrillator surgery in patients with an implanted left ventricular assist device safe under uninterrupted oral anticoagulation?
- Authors
Vondran, Maximilian; von Aspern, Konstantin; Garbade, Jens; Lässing, Johannes; Kiefer, Philipp; Rastan, Ardawan Julian; Borger, Michael Andrew; Schroeter, Thomas
- Abstract
Background: Implantable cardioverter‐defibrillator (ICD) surgery in patients with implanted left ventricular assist devices (LVAD) is associated with an increased risk of bleeding complications because of the need to ensure that these patients are adequately anticoagulated. Our study aimed to evaluate the safety of our new strategy of uninterrupted oral anticoagulation compared to heparin‐bridging during the surgical interval. Methods: Between January 2009 and January 2020, 116 patients with LVAD underwent ICD surgery. Since January 2015, 60 patients were operated under continued sufficient oral anticoagulation with a vitamin k antagonist (VKA group). Fifty‐six patients underwent a heparin‐bridging regimen (heparin group). Demographics, perioperative data, complications, and mortality were analyzed. Results: Bleeding complications attributable to the surgical intervention occurred more often (19.6% vs. 10.0%, p = 0.142) and at a higher rate of re‐exploratory surgery (14.3% vs. 5.0%, p = 0.088) in the heparin group without reaching statistical significance. Moreover, the heparin group patients' postoperative total length of stay was 10 days longer (17.8 ± 23.8 days vs. 8.3 ± 9.5 days, p = 0.007). There were no procedure‐related deaths, no thromboembolic events, and no LVAD‐related thrombosis. Conclusion: Our strategy of uninterrupted oral anticoagulation is safe and results in a reduction by more than half the number of days in hospital without an increase in adverse events.
- Subjects
HEART assist devices; IMPLANTABLE cardioverter-defibrillators; ANTICOAGULANTS; CARDIAC pacing; HEPARIN; SURGICAL complications
- Publication
Artificial Organs, 2022, Vol 46, Issue 8, p1564
- ISSN
0160-564X
- Publication type
Article
- DOI
10.1111/aor.14217