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- Title
"Burned-out" tumour of the testis with metastasis to the retroperitoneal lymph node.
- Authors
Kajo, Karol; Kajo, Michal; Macháleková, Katarína; Palaj, Július; Mečiarová, Iveta; Zuzák, Peter; Tvrdík, Emil
- Abstract
The term "burned-out tumour" refers to a rare clinical entity that represents a complete spontaneous regression of previously untreated testicular cancer with metastases in the retroperitoneum, mediastinum, lymph nodes, lung or liver. We describe the case of a 55-year-old patient with pain in the right lumbar region, in which the CT scan disclosed a tumour mass in the retroperitoneum (sized 70 × 55 × 90 mm), and ultrasonography revealed structural changes in the lower pole of the right testicle. First, the patient underwent a right-sided orchiectomy with histological finding of a scar in the testicle without distinct tumour changes, followed by radical resection of the retroperitoneal tumour, which histology proved to be a metastasis of seminoma in the lymph node. Consequently, the histology in the testis was re-evaluated and determined to be a completely regressed testicular tumour - "burned-out tumour." Subsequently, patient underwent adjuvant chemotherapy. The pathogenesis of "burned-out" tumours are comprises mainly of immunological factors, ischemia represents another, although less probable cause. Prognosis of "burned-out" tumours in cases of seminomatous germ cell tumours is comparable with those of primary testicular tumours.
- Publication
Czech Urology / Ceska Urologie, 2014, Vol 18, Issue 2, p138
- ISSN
1211-8729
- Publication type
Article