We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Efficacy of different varieties of medical cannabis in relieving symptoms.
- Authors
Wan, Bo Angela; Diaz, Patrick; Blake, Alexia; Chan, Stephanie; Wolt, Amiti; Zaki, Pearl; Liying Zhang; Slaven, Marissa; Shaw, Erynn; DeAngelis, Carlo; Lam, Henry; Ganesh, Vithusha; Malek, Leila; Chow, Edward; O'Hearn, Shannon
- Abstract
Traditionally, cultivars of Cannabis sativa L. have been divided into sub-species based on their morphological properties, metabolic profile, and geographical origin. Interbreeding subspecies renders hybrids characterised by varying sativa and indica profiles, and unique cannabinoid ratios. As cannabinoid compounds like tetrahydro-cannabinol (THC) and cannabidiol (CBD) are thought to be primarily responsible for the physiological effects of cannabis, unique strain profiles may provide different therapeutic benefits suitable for managing different symptoms and conditions. This study aims to assess the efficacy of different cannabis varieties in patients using medical cannabis from one Canadian licensed provider. Information pertaining to current medical conditions, symptoms, and quality of life were collected through a voluntary online survey administered to patients after registration, and at 4 and 10 month follow-up intervals. 837 patients provided information about their experience with medical cannabis at 4-month follow-up. Patients reported that the variety MidnightMR (sativa-leaning, 8-11% THC, 11-14% CBD) was most efficacious for reducing pain (27.4%), and that LuminariumMR (very sativa-dominant, 25-28% THC, 0% CBD) was effective for managing both anxiety disorder (30.4%) and depression (35.5%). Patients most commonly attributed improvements in sleep (29.0%), appetite (24.8%), and bowel function (24.6%) to MidnightMR, improvements in concentration (22.0%) to CognitivaMR (sativa-leaning, 15-18% THC, 0% CBD), and improvements in sexual function (26.5%) to LuminariumMR. The efficacy of different cannabis varieties in managing various symptoms should be further investigated in a controlled clinical setting, to enable patients and physicians to make informed decisions on which varieties are best suited to achieve optimal symptom management.
- Subjects
ANXIETY prevention; PREVENTION of mental depression; PREVENTIVE medicine; PAIN; QUALITY of life; SURVEYS; MEDICAL marijuana; TREATMENT effectiveness
- Publication
Journal of Pain Management, 2017, Vol 10, Issue 4, p375
- ISSN
1939-5914
- Publication type
Article