We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
CORRELATION BETWEEN THE ESTIMATED TOTAL THIOSULFINATES CONTENT AND ANTIPLATELET ACTIVITY OF THREE DIFFERENT VARIETIES A. CEPA.
- Authors
SAPLONŢAI-POP, ANIELA; MOLDOVAN, MARIOARA; OPREAN, RADU; ORASAN, OLGA; SAPLONTAI, STEFAN; IONESCU, CORINA
- Abstract
The present study aims to establish a correlation between the estimated thiosulfinate compound content of Allium cepa L. (A. cepa) juices and their antiplatelet activity. The juices were obtained from three different varieties of A. cepa, cultivated in three different regions of Romania. The thiosulfinate compound content was estimated using a spectrophotometric method, based on the reaction with 4-mercapto-pyridine (a chromogenic thiol, with a maximum absorbance coefficient at 324 nm). The constant of the reaction kinetic curve was obtained by overlapping experimental data with an exponential function of first degree. The antiplatelet activity of the mentioned juices was measured by using in vitro tests with platelet rich plasma (PRP) obtained from blood collected from healthy human people, with arachidonic acid as platelet agonist. A statistically significant direct proportionality between the estimated thiosulfinate compound content and the anti-platelet activity of the tested A. cepa juices was established.
- Subjects
STATISTICAL correlation; PLATELET aggregation inhibitors; ONION varieties; SPECTROPHOTOMETRY; PYRIDINE; BLOOD collection; ARACHIDONIC acid
- Publication
Studia Universitatis Babes-Bolyai, Chemia, 2014, Vol 59, Issue 4, p39
- ISSN
1224-7154
- Publication type
Article