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- Title
Hypercholesterolemia Among Apparently Healthy University Students.
- Authors
Shawar, Said M.; Al-bati, Neda A.; Al-mahameed, Ali; Nagalla, Das S.; Obeidat, Mohammed
- Abstract
Background: Hypercholesterolemia (HC) is a major risk factor in the development of coronary heart disease (CHD). Serum cholesterol is directly related to complications and mortalities associated with heart diseases. There are a few studies that describe HC among youths in the Arab Gulf countries. We sought to evaluate HC among young healthy university students to assess their risk of developing CHD. Methods: Lipid profile of 166 students between the ages of 16- 30 years (Mean: 20.49±2.96) were examined and blood glucose, total protein, albumin, thyroid stimulating hormone (TSH) and the inflammation marker high sensitivity CRP (hsCRP) were determined. Each volunteer filled a questionnaire about her/his lifestyle and personal and family medical histories and height and weight were measured to determine body mass index (BMI). The data were analyzed using SPSS version 17. Chi-Square was used to determine the relation between categorical variables. A p-value <0.05 was considered statistically significant. Results: According to the American Heart Association criteria, 44 (26.5%) students were identified with primary hypercholesterolemia (PHC) in the first testing round. After proper health counseling, the same tests were repeated after 2-3 weeks in all 44 hypercholesterolemic students. We found only 26 (15.6%) of them to be hypercholesterolemic. There was a significant relation between high total cholesterol (TC) and high TC/HDLC, as well as high or very high hsCRP and high TC/HDLC (both, p<0.001). Males tend to have higher TC/HDLC and hsCRP than females (both p0.002 and 0.005, respectively). Family history of CHD was found in 8 students and obesity was recorded in 5 volunteers. Conclusion: The results necessitate further studies in determining the cause of PHC. We predict a genetic element contributing to the high percentage of PHC in the current study.
- Subjects
ARABIAN Peninsula; BLOOD testing; CORONARY heart disease risk factors; HYPERCHOLESTEREMIA diagnosis; BLOOD sugar; C-reactive protein; CHI-squared test; COLLEGE students; HIGH density lipoproteins; HORMONES; LIPIDS; HYPERCHOLESTEREMIA; LOW density lipoproteins; OBESITY; PROTEINS; QUESTIONNAIRES; SERUM albumin; SEX distribution; BODY mass index; FAMILY history (Medicine); DATA analysis software; DESCRIPTIVE statistics; DISEASE complications; DISEASE risk factors
- Publication
Oman Medical Journal, 2012, Vol 27, Issue 4, p274
- ISSN
1999-768X
- Publication type
Article
- DOI
10.5001/omj.2012.69