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- Title
BRUCELOSE OSTEO-ARTICULAR: UM RETRATO DOS ÚLTIMOS 10 ANOS.
- Authors
Santiago, T.; Rovisco, J.; Silva, J.; Silva, J. A. Pereira da
- Abstract
Objectives: Characterize Osteoarticular Bruceilosis in the University Hospital of Coimbra (HUC) in the past decade. Material and Methods: A retrospective study of the cases diagnosed between January/2000 and December/2009 in the HUC. Results: Ninety patients were admitted with the diagnosis of brucellosis in our hospital, of whom 44 (49%; 18 men; 26 women, mean 49.5 years) had osteoarticular complications. Twenty-five (45%) patients had a positive epidemiological context. The most frequent clinical manifestation was local pain (73%) followed by polyarthralgias and constitutional symptoms. The C-reactive protein was the inflammatory marker most often increased (82%). The Rose Bengala test was positive in 42 patients, and a Wright's sero-aglutination above than 1 / 160 was detected in 28 patients. An etiologic agent was isolated in 28 (64%) patients, with 70% of positive blood cultures. The imaging procedure of choice was magnetic resonance imaging (MRI) (46%). The osteo-articular manifestation most frequent was spondylodiscitis (57%) with a lumbosacral involvement in 40%. Ali patients completed antibiotic therapy. One patient underwent surgery to drain the abscess. Patients had an average length of admission of 28.3 days, with a good outcome in 60%, and a reasonable outcome in 20%, despite 20% of the patients lost follow-up. Conclusions: Brucellosis is a disease of obligatory declaration not eradicated in Portugal, with a great impact on socio-economic and public health. So, this epidemiological knowledge of brucellosis cases, allows an early intervention and therapy.
- Subjects
PORTUGAL; BRUCELLOSIS; BONE diseases; RETROSPECTIVE studies; PUBLIC health; EPIDEMIOLOGY; SPONDYLITIS; MAGNETIC resonance imaging
- Publication
Acta Reumatológica Portuguesa, 2011, Vol 36, Issue 2, p120
- ISSN
0303-464X
- Publication type
Article