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Zeitaufgelöst und markerfrei gemessene ligandeninduzierte Konformationsänderungen von HSP90 – hin zu einem Konformationsaktivitätsscreening für die Wirkstoffentwicklung.
- Published in:
- Angewandte Chemie, 2018, v. 130, n. 31, p. 10103, doi. 10.1002/ange.201802603
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- Publication type:
- Article
Raman‐mikrospektroskopischer Nachweis für den Metabolismus eines Tyrosinkinase‐Inhibitors, Neratinib, in Krebszellen.
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- Angewandte Chemie, 2018, v. 130, n. 24, p. 7370, doi. 10.1002/ange.201803394
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- Article
[FeFe]-Hydrogenase with Chalcogenide Substitutions at the H-Cluster Maintains Full H<sub>2</sub> Evolution Activity.
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- Angewandte Chemie, 2016, v. 128, n. 29, p. 8536, doi. 10.1002/ange.201511896
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- Article
Label-free vibrational imaging of different Aβ plaque types in Alzheimer's disease reveals sequential events in plaque development.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-01091-5
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- Article
Amyloid blood biomarker detects Alzheimer's disease.
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- EMBO Molecular Medicine, 2018, v. 10, n. 5, p. 1, doi. 10.15252/emmm.201708763
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- Article
Ligand‐Induced Conformational Changes in HSP90 Monitored Time Resolved and Label Free—Towards a Conformational Activity Screening for Drug Discovery.
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- Angewandte Chemie International Edition, 2018, v. 57, n. 31, p. 9955, doi. 10.1002/anie.201802603
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- Article
Raman Microspectroscopic Evidence for the Metabolism of a Tyrosine Kinase Inhibitor, Neratinib, in Cancer Cells.
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- Angewandte Chemie International Edition, 2018, v. 57, n. 24, p. 7250, doi. 10.1002/anie.201803394
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- Publication type:
- Article
[FeFe]-Hydrogenase with Chalcogenide Substitutions at the H-Cluster Maintains Full H<sub>2</sub> Evolution Activity.
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- Angewandte Chemie International Edition, 2016, v. 55, n. 29, p. 8396, doi. 10.1002/anie.201511896
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- Publication type:
- Article
Early Formation of the Ion-Conducting Pore in Channelrhodopsin-2.
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- Angewandte Chemie International Edition, 2015, v. 54, n. 16, p. 4953, doi. 10.1002/anie.201410180
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- Publication type:
- Article
Back Cover: Early Formation of the Ion-Conducting Pore in Channelrhodopsin-2 (Angew. Chem. Int. Ed. 16/2015).
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- Angewandte Chemie International Edition, 2015, v. 54, n. 16, p. 4970, doi. 10.1002/anie.201502275
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- Publication type:
- Article
A structure‐based fluid biomarker for the differential diagnosis of early‐stage neurodegenerative diseases measured by the immuno‐infrared‐sensor (iRS).
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082847
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- Article
High cholesterol levels change the association of biomarkers of neurodegenerative diseases with dementia risk: Findings from a population‐based cohort.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 7, p. 2913, doi. 10.1002/alz.12933
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- Article
Amyloid‐beta misfolding and GFAP predict risk of clinical Alzheimer's disease diagnosis within 17 years.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 3, p. 1020, doi. 10.1002/alz.12745
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- Article
Association of plasma biomarkers, p‐tau181, glial fibrillary acidic protein, and neurofilament light, with intermediate and long‐term clinical Alzheimer's disease risk: Results from a prospective cohort followed over 17 years.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 1, p. 25, doi. 10.1002/alz.12614
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- Article
Kidney function is associated to Alzheimer's related blood biomarkers (NfL, P‐tau181, and GFAP) but not dementia risk in a community‐based cohort followed over 17 years.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.069248
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- Article
The association between plasma biomarkers, p‐tau181, glial fibrillary acidic protein, and neurofilament light and clinical AD risk: Results from prospective cohort study followed over 17 years.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057547
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- Article
Generation of mid‐region murine monoclonal antibodies against multiple structural isoforms of amyloid‐beta by hybridoma technology: Biomarkers (non‐neuroimaging) / plasma/serum/urine biomarkers.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043577
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- Article
Investigating Aβ plaque development using FTIR micro‐spectroscopy on native postmortem human brain tissue: Human neuropathology/imaging‐pathologic correlations.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043289
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- Publication type:
- Article
Throughput optimized immuno‐infrared‐assay for Alzheimer's disease diagnosis: Biomarkers (non‐neuroimaging) / Method development and/or quality control.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043093
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- Publication type:
- Article
Prediction of Alzheimer's disease diagnosis within 14 years through Aβ misfolding in blood plasma compared to APOE4 status, and other risk factors.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 2, p. 283, doi. 10.1016/j.jalz.2019.08.189
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- Article
Structural Basis of Slow Activation Gating in the Cardiac I<sub>Ks</sub> Channel Complex.
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- Cellular Physiology & Biochemistry (Karger AG), 2011, v. 27, n. 5, p. 443, doi. 10.1159/000329965
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- Publication type:
- Article
Time-resolved spectroscopic and electrophysiological data reveal insights in the gating mechanism of anion channelrhodopsin.
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- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02101-5
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- Article
Genetic predisposition, Aβ misfolding in blood plasma, and Alzheimer's disease.
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- Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01380-0
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- Article
Genetic predisposition, Aβ misfolding in blood plasma, and Alzheimer's disease.
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- Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01380-0
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- Publication type:
- Article
Amyloid-β misfolding as a plasma biomarker indicates risk for future clinical Alzheimer's disease in individuals with subjective cognitive decline.
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- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-020-00738-8
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- Article
A representation learning approach for recovering scatter‐corrected spectra from Fourier‐transform infrared spectra of tissue samples.
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- Journal of Biophotonics, 2021, v. 14, n. 3, p. 1, doi. 10.1002/jbio.202000385
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- Article
Grayscale representation of infrared microscopy images by extended multiplicative signal correction for registration with histological images.
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- Journal of Biophotonics, 2020, v. 13, n. 8, p. 1, doi. 10.1002/jbio.201960223
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- Article
An open‐source code for Mie extinction extended multiplicative signal correction for infrared microscopy spectra of cells and tissues.
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- Journal of Biophotonics, 2019, v. 12, n. 8, p. N.PAG, doi. 10.1002/jbio.201800415
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- Article
Shape decomposition algorithms for laser capture microdissection.
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- Algorithms for Molecular Biology, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13015-021-00193-6
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- Article
Light-induced reactions of Escherichia coli DNA photolyase monitored by Fourier transform infrared spectroscopy.
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- FEBS Journal, 2005, v. 272, n. 8, p. 1855, doi. 10.1111/j.1742-4658.2005.04617.x
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- Article
In vitro prediction of the efficacy of molecularly targeted cancer therapy by Raman spectral imaging.
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- Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 27, p. 8321, doi. 10.1007/s00216-015-8875-z
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- Article
Cover Picture: Surface-Attached Polyhistidine-Tag Proteins Characterized by FTIR Difference Spectroscopy (ChemPhysChem 11/2012).
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- ChemPhysChem, 2012, v. 13, n. 11, p. 2617, doi. 10.1002/cphc.201290051
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- Article
Surface-Attached Polyhistidine-Tag Proteins Characterized by FTIR Difference Spectroscopy.
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- ChemPhysChem, 2012, v. 13, n. 11, p. 2649, doi. 10.1002/cphc.201200358
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- Article
How Does a Membrane Protein Achieve a Vectorial Proton Transfer Via Water Molecules?
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- ChemPhysChem, 2008, v. 9, n. 18, p. 2772, doi. 10.1002/cphc.200800703
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- Article
Proteins in Action Monitored by Time-Resolved FTIR Spectroscopy.
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- ChemPhysChem, 2005, v. 6, n. 5, p. 881, doi. 10.1002/cphc.200400504
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- Article
Die frühe Entstehung der ionenleitenden Pore in Channelrhodopsin-2.
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- Angewandte Chemie, 2015, v. 127, n. 16, p. 5037, doi. 10.1002/ange.201410180
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- Publication type:
- Article
Rücktitelbild: Die frühe Entstehung der ionenleitenden Pore in Channelrhodopsin-2 (Angew. Chem. 16/2015).
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- Angewandte Chemie, 2015, v. 127, n. 16, p. 5054, doi. 10.1002/ange.201502275
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- Publication type:
- Article
Titelbild: Vorhersage der Ligandenerkennung in einem Geruchsrezeptor durch Kombination von ortsgerichteter Mutagenese und dynamischer Homologie-Modellierung (Angew. Chem. 5/2012).
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- Angewandte Chemie, 2012, v. 124, n. 5, p. 1105, doi. 10.1002/ange.201107509
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- Publication type:
- Article
Vorhersage der Ligandenerkennung in einem Geruchsrezeptor durch Kombination von ortsgerichteter Mutagenese und dynamischer Homologie-Modellierung.
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- Angewandte Chemie, 2012, v. 124, n. 5, p. 1300, doi. 10.1002/ange.201103980
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- Publication type:
- Article
Gerichteter Protonentransfer in Membranproteinen mittels protonierter proteingebundener Wassermoleküle: eine Protonendiode.
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- Angewandte Chemie, 2010, v. 122, n. 38, p. 7041, doi. 10.1002/ange.201001243
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- Article
Advances in Digital Pathology: From Artificial Intelligence to Label-Free Imaging.
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- Visceral Medicine, 2021, v. 37, n. 6, p. 482, doi. 10.1159/000518494
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- Publication type:
- Article
Spatial and molecular resolution of diffuse malignant mesothelioma heterogeneity by integrating label-free FTIR imaging, laser capture microdissection and proteomics.
- Published in:
- Scientific Reports, 2017, p. 44829, doi. 10.1038/srep44829
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- Publication type:
- Article
Label-free identification of myopathological features with coherent anti-Stokes Raman scattering.
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- 2018
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- Publication type:
- journal article
Water dynamics simulation as a tool for probing proton transfer pathways in a heptahelical membrane protein.
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- Proteins, 2005, v. 58, n. 3, p. 528, doi. 10.1002/prot.20343
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- Article
Update on CSF Biomarkers in Parkinson's Disease.
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- Biomolecules (2218-273X), 2022, v. 12, n. 2, p. 329, doi. 10.3390/biom12020329
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- Publication type:
- Article
Unravelling the mechanism of dual-specificity GAPs.
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- EMBO Journal, 2010, v. 29, n. 7, p. 1205, doi. 10.1038/emboj.2010.20
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- Article
Fully automated registration of vibrational microspectroscopic images in histologically stained tissue sections.
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- BMC Bioinformatics, 2015, v. 16, p. 1, doi. 10.1186/s12859-015-0804-9
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- Publication type:
- Article
Similarity maps and hierarchical clustering for annotating FT-IR spectral images.
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- BMC Bioinformatics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2105-14-333
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- Article
Front Cover: Lamprey Parapinopsin ("UVLamP"): a Bistable UV‐Sensitive Optogenetic Switch for Ultrafast Control of GPCR Pathways (ChemBioChem 5/2020).
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- ChemBioChem, 2020, v. 21, n. 5, p. 572, doi. 10.1002/cbic.201900720
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- Publication type:
- Article
Lamprey Parapinopsin ("UVLamP"): a Bistable UV‐Sensitive Optogenetic Switch for Ultrafast Control of GPCR Pathways.
- Published in:
- ChemBioChem, 2020, v. 21, n. 5, p. 612, doi. 10.1002/cbic.201900485
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- Publication type:
- Article