We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Evans Syndrome with Acute Kidney Injury.
- Authors
Hanfei Lin; Kefei Wu; Weidai Zhang; Guili Lin; Chudan Cai
- Abstract
Evans syndrome is a rare syndrome associated with the simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and idiopathic thrombocytopenic purpura (ITP). Furthermore, acute kidney injury (AKI) is a syndrome characterized by the rapid loss of kidney excretory function and is most often secondary to extrarenal events. However, AKI has rarely been recorded in Evans syndrome without systemic autoimmune disease and malignant tumors of the blood and lymphatic system. Herein, we report the case of a patient who exhibited Evans syndrome presenting with AKI. A 73-year-old woman presented with diarrhea, anuria, low platelet count, and a progressive increase in blood urea nitrogen and serum creatinine as well as anemia with a positive direct Coombs test. We excluded hemolytic uremic syndrome, ITP, and leukemia. Treatment with antibiotics, rehydration therapy, and hemodialysis resulted in partial remission. Thus, we diagnosed the patient with Evans syndrome presenting with AKI. The patient was successfully treated by the addition of steroid treatment. When AKI presents with hemolysis and thrombocytopenia, physicians should consider Evans syndrome, which can be appropriately treated when detected early.
- Subjects
TREATMENT of acute kidney failure; ANTIBIOTICS; STEROID drugs; THROMBOPENIC purpura diagnosis; ACUTE kidney failure; ANURIA; CREATININE; DIARRHEA; FLUID therapy; HEMODIALYSIS; AUTOIMMUNE hemolytic anemia; NITROGEN compounds; THROMBOPENIC purpura; UREA; DISEASE remission; EARLY diagnosis; PLATELET count; SYMPTOMS
- Publication
Archives of Iranian Medicine (AIM), 2019, Vol 22, Issue 6, p336
- ISSN
1029-2977
- Publication type
Article