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- Title
Harmonic imaging improves estimation of left ventricular mass.
- Authors
Spratt, James; Leslie, Stephen; White, Audrey; Fenn, Lynn; Turnbull, Colin; Northridge, David
- Abstract
Objectives: To assess the effect of tissue harmonic imaging (THI) on assessment of left ventricular mass index (LVMI) measurements by M-mode trans-thoracic echocardiography, when compared with magnetic resonance imaging (MRI). Methods: 20 hypertensive male subjects were studied. LVMI was measured in all subjects by both gradient-echo MRI (Lscelsint Prestige 1.9 T) and by transthoracic echocardiography (ATL HDI 5000). M-mode echocardiography recordings were taken for each patient, two with fundamental imaging (FI) and two using THI in a randomised order and the images unlabelled. Recordings were analysed off-line, by a blinded observer. LVMI by MRI was calculated using Simpson's rule on serial short axis slices of 8 mm thickness. Data are expressed as mean ± SD. Results: There was a difference in LVMI measurements between FI and THI (LVMI) (79 ± 20 vs. 93 ± 25 g2; p < 0.001). A lower mean difference was obtained by THI, compared to FI, when compared with MRI (2 ± 15 vs. −32 ± 22 g2; p < 0.001) suggesting that FI underestimates LVMI. Inter-observer variability was similar between THI and FI (4.5 ± 15 vs. 6.4 ± 15 g2; p = 0.46). Conclusion: In hypertensive males, M-mode echo derived from FI underestimated LVMI. These results imply that widely accepted reference ranges for LVMI using FI are not applicable when THI is used.
- Publication
International Journal of Cardiovascular Imaging, 2004, Vol 20, Issue 2, p107
- ISSN
1569-5794
- Publication type
Article
- DOI
10.1023/B:CAIM.0000014047.59389.1f