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- Title
Parallel domestication of the Shattering1 genes in cereals.
- Authors
Lin, Zhongwei; Li, Xianran; Shannon, Laura M; Yeh, Cheng-Ting; Wang, Ming L; Bai, Guihua; Peng, Zhao; Li, Jiarui; Trick, Harold N; Clemente, Thomas E; Doebley, John; Schnable, Patrick S; Tuinstra, Mitchell R; Tesso, Tesfaye T; White, Frank; Yu, Jianming
- Abstract
A key step during crop domestication is the loss of seed shattering. Here, we show that seed shattering in sorghum is controlled by a single gene, Shattering1 (Sh1), which encodes a YABBY transcription factor. Domesticated sorghums harbor three different mutations at the Sh1 locus. Variants at regulatory sites in the promoter and intronic regions lead to a low level of expression, a 2.2-kb deletion causes a truncated transcript that lacks exons 2 and 3, and a GT-to-GG splice-site variant in the intron 4 results in removal of the exon 4. The distributions of these non-shattering haplotypes among sorghum landraces suggest three independent origins. The function of the rice ortholog (OsSh1) was subsequently validated with a shattering-resistant mutant, and two maize orthologs (ZmSh1-1 and ZmSh1-5.1+ZmSh1-5.2) were verified with a large mapping population. Our results indicate that Sh1 genes for seed shattering were under parallel selection during sorghum, rice and maize domestication.
- Subjects
CROPS; PLANT cytogenetics; GENETIC engineering of crops; GENE expression; TRANSCRIPTION factors; SORGHUM (Genus); DELETION mutation
- Publication
Nature Genetics, 2012, Vol 44, Issue 6, p720
- ISSN
1061-4036
- Publication type
Article
- DOI
10.1038/ng.2281