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- Title
Mind the Gap between the Endothelium and E3 Ubiquitin Ligase: TRIM21 Is a Viable Therapeutic Target in Sepsis-induced Endothelial Dysfunction.
- Authors
Natarajan, Viswanathan
- Abstract
An editorial is presented on difference between the Endothelium and E3 Ubiquitin Ligase. It examines the Acute lung injury (ALI) due to sepsis or mechanical ventilation, a refractory lung disease that is characterized by severe hypoxemia and unacceptably high morbidity and mortality; and evidence that TRIM21 plays a role in LPSmediated lung inflammation and endothelial dysfunction.
- Subjects
ENDOTHELIUM; ENDOTHELIUM diseases; UBIQUITIN ligases; LUNG injuries; LUNG injury treatment; VENTILATION
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2019, Vol 61, Issue 6, p676
- ISSN
1044-1549
- Publication type
Article
- DOI
10.1165/rcmb.2019-0161ed