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- Title
Lepra. Clasificación y cuadro clínico.
- Authors
Torres Guerrero, Edoardo; Vargas Martínez, Felipe; Atoche Diéguez, Carlos Enrique; Arrazola, Jisel; Arenas Guzmán, Roberto
- Abstract
Before 1943, leprosy patients were classified just by the clinical appearance of their lesions. After International Leprosy Congress, celebrated in Madrid in 1953, current classification was accepted and it includes several parameters such as: clinic, baciloscopic, immunologic and histologic. Since 1960, leprosy has been considered an immunologic model, where "immunologic dichotomy" is present. In one pole, lepromatous leprosy has immunological detriment with poor cell mediated immunity. In the other one, tuberculoid leprosy increased the cellular response. The classification includes two polar types (lepromatous and tuberculoid), two groups of cases (indeterminate and borderline); and two types of reaction: type II (erythema nodosum, erythema multiforme and Lucio's phenomenon), and type I (reversal reaction). Clinical lesions can be identified in almost every organ and system (mainly skin, mucous membranes and peripheral nervous system), only central nervous system is spared.
- Subjects
HANSEN'S disease patients; BIOLOGICAL classification; INTERNATIONAL Leprosy Congress; IMMUNOLOGY; PERIPHERAL nervous system; MYCOBACTERIUM leprae
- Publication
Dermatología Revista Mexicana, 2012, Vol 56, Issue 1, p53
- ISSN
0185-4038
- Publication type
Article