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- Title
Aqueous Extracts of Rhizopus oryzae Induced Nitric Oxide Production in Rat Hepatocyte Cell Line RLN-10.
- Authors
Takehito SUZUKI; Mayuko UCHIDA; Yuji TAKEDA; Chiemi MORI; Atsushi ONUKI; Yoko MIYAZAKI; Ken ONDA; Setsuo USHIKOSHI; Kotaro SHITORI; Kazuaki TANAKA; Hidetoshi MORITA; Tatsuya TAKIZAWA
- Abstract
In this article, the authors focus on the role of Rhizopus oryzae, a fungus, in the production on nitric oxide in rat hepatocyte cell line RLN-10. They inform that aqueous extract of the fungus induces diaminofluorescein-FM diacetate staining in the cells and the accumulation of nitrite in cell culture medium. They mention that the fungus also increases nuclear translocation of nuclear factor-kappa (NF-kappa) B p65 after lipopolysaccharide treatment, a potent activator of NF-kappa B.
- Subjects
RHIZOPUS oryzae; NITRIC oxide; LABORATORY rats; DIACETATES; NITRITES; NF-kappa B genetics; PHYSIOLOGICAL effects of lipopolysaccharides
- Publication
Bioscience, Biotechnology & Biochemistry, 2013, Vol 77, Issue 7, p1384
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1271/bbb.120951