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- Title
Functional connectivity of motor cortical network in patients with brachial plexus avulsion injury after contralateral cervical nerve transfer: a resting-state fMRI study.
- Authors
Yu, Aihong; Wang, Shufeng; Cheng, Xiaoguang; Liang, Wei; Bai, Rongjie; Xue, Yunhao; Li, Wenjun
- Abstract
Introduction: The purpose of this study is to assess the functional connectivity of the motor cortical network in patients with brachial plexus avulsion injury (BPAI) after contralateral C7 nerve transfer, using resting-state functional magnetic resonance imaging (RS-fMRI). Methods: Twelve patients with total brachial plexus root avulsion underwent RS-fMRI after contralateral C7 nerve transfer. Seventeen healthy volunteers were also included in this fMRI study as controls. The hand motor seed regions were defined as region of interests in the bilateral hemispheres. The seed-based functional connectivity was calculated in all the subjects. Differences in functional connectivity of the motor cortical network between patients and healthy controls were compared. Results: The inter-hemispheric functional connectivity of the M1 areas was increased in patients with BPAI compared with the controls. The inter-hemispheric functional connectivity between the supplementary motor areas was reduced bilaterally. Conclusions: The resting-state inter-hemispheric functional connectivity of the bilateral M1 areas is altered in patients after contralateral C7 nerve transfer, suggesting a functional reorganization of cerebral cortex.
- Subjects
BRAIN physiology; CEREBRAL cortex; MEDIAN nerve surgery; BIRTH injuries; BRACHIAL plexus; BRAIN mapping; CEREBRAL hemispheres; COMPARATIVE studies; MAGNETIC resonance imaging; HEALTH outcome assessment; NEURAL pathways; BRACHIAL plexus neuropathies
- Publication
Neuroradiology, 2017, Vol 59, Issue 3, p247
- ISSN
0028-3940
- Publication type
Article
- DOI
10.1007/s00234-017-1796-0