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- Title
Usefulness of the Post-Vascular Phase of Contrast-Enhanced Ultrasonography with Sonazoid in the Evaluation of Gross Types of Hepatocellular Carcinoma.
- Authors
Hatanaka, Kinuyo; Chung, Hobyung; Kudo, Masatoshi; Haji, Seiji; Minami, Yasunori; Maekawa, Kiyoshi; Hayaishi, Sousuke; Nagai, Tomoyuki; Takita, Masahiro; Kudo, Kanae; Ueda, Taisuke; Tatsumi, Chie; Kitai, Satoshi; Ishikawa, Emi; Yada, Norihisa; Inoue, Tatsuo; Hagiwara, Satoru; Ueshima, Kazuomi
- Abstract
Objective: The purpose of this study was to assess the usefulness of post-vascular phase (PVP) images of contrast-enhanced ultrasonography (CE-US) in the evaluation of the gross types of hepatocellular carcinoma (HCC) that is closely related to the malignant potential of the tumor. Methods: A total of 29 patients with 40 HCCs of <5 cm in diameter, who underwent hepatic resection, were enrolled. The gross type of the tumor was evaluated using real-time scanning during the PVP of CE-US with Sonazoid prior to surgery. The tumors were classified into three types based on the macroscopic classification of the Liver Cancer Study Group of Japan: single nodular (SN) type, single nodular with extranodular growth (SNEG) type, and confluent multinodular (CMN) type. The ability of CE-US to correctly depict the gross type of HCC was evaluated. Results: 26 tumors were macroscopically diagnosed as the SN type, 11 tumors as the SNEG type, and 3 tumors as the CMN type. The sensitivity, specificity and accuracy of CE-US were 96, 80 and 90%, respectively. Conclusion: The PVP image of CE-US with Sonazoid is a useful tool in the evaluation of the gross type of HCC and is considered essential in deciding treatment strategy. Copyright © 2010 S. Karger AG, Basel
- Subjects
LIVER cancer; CONTRAST-enhanced ultrasound; NODULAR disease; LIVER tumors; LIVER surgery
- Publication
Oncology, 2010, Vol 78, p53
- ISSN
0030-2414
- Publication type
Article
- DOI
10.1159/000315231