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- Title
Merkezimizde cerrahi geçiren down sendromu tanılı hastalarımızın kardiyak patolojileri ve cerrahi sonuçları.
- Authors
Çetin, Recep; Sarısoy, Özlem; Dedemoğlu, Mehmet; Öner, Taliha; Karacan, Mehmet; Vuran, Can
- Abstract
Objective: Down syndrome (DS) is one of the most prevalent chromosomal disorders. It is often comorbid with congenital heart diseases (CHD). In this study, we aimed to assess the types, complications, and course of CHD in patients with DS who have been treated in our Pediatric Cardiovascular Surgery (CVS) clinic. Material and Methods: Between September 2019 and November 2023, all patients who received inpatient treatment in the ÜEAH Pediatric CVS service were screened, and the records of 66 patients who were found to have DS were retrospectively investigated. Results: Considering the cardiac defects of the patients, it was seen that 31 patients had complete atrioventricular septal defect (AVSD), 22 patients had ventricular septal defect (VSD), 4 patients had intermediate AVSD, 3 patients had Fallot-type AVSD, 3 patients had tetralogy of Fallot, and 3 patients had unbalanced AVSD in single ventricular physiology. One or more of the complications such as sepsis, arrhythmia, pneumothorax, and pleural effusion were observed in 19 (28.8%) of the patients. Pleural effusion was observed in 5 patients. Post-operative arrhythmia was observed in 7 patients (10.6%). The mortality rate of the patients was 12.1%. When examining the causes of mortality of these 8 patients, it was seen that 4 of them had pneumonia + sepsis due to long-term hospitalization, whereas the other 4 had low cardiac output syndrome (LCOS) and sepsis. 88% of the deceased patients were admitted to the clinic with heart failure and diagnosed with AVSD. Conclusion: In this study, the post-surgical hospital stay of DS patients was relatively shorter (mean 10.6 days) than the length of stay (mean 14 days) in other studies. Due to several factors such as higher rates of infection in patients with DS during the post-surgical stage, higher risks of pulmonary hypertension (PHT) emerging from the significant left-to-right shunt, nutritional problems, muscle hypotonia, obstructive sleep apnea syndrome, and thyroid malfunction, the rates of hospital stay and mortality rates in DS patients with CHD are relatively higher.
- Subjects
DIAGNOSIS of Down syndrome; HEART disease complications; CONGENITAL heart disease; SURGERY; PATIENTS; SURGICAL clinics; TREATMENT effectiveness; CHROMOSOME abnormalities; PNEUMOTHORAX; DESCRIPTIVE statistics; CAUSES of death; ARRHYTHMIA; ENDOCARDIAL cushion defects; SEPSIS; SLEEP apnea syndromes; LENGTH of stay in hospitals; CARDIAC surgery
- Publication
Ümraniye Pediatri Dergisi, 2023, Vol 3, Issue 3, p164
- ISSN
2757-7074
- Publication type
Article
- DOI
10.14744/upd.2023.85570