Back to matchesWe found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleTemsirolimus.AuthorsRini, Brian; Kar, Santwana; Kirkpatrick, PeterAbstractTemsirolimus (Torisel; Wyeth) is an inhibitor of the kinase mTOR (mammalian target of rapamycin). It was approved by the US FDA for the treatment of advanced renal cell carcinoma in May 2007.SubjectsRAPAMYCIN; RENAL cell carcinoma; DRUG therapy; CYTOKINES; INTERFERONS; VASCULAR endothelial growth factors; UNITED States. Food &; Drug AdministrationPublicationNature Reviews Drug Discovery, 2007, Vol 6, Issue 8, p599ISSN1474-1776Publication typeArticleDOI10.1038/nrd2382