Back to matchesWe found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleGenetic and epigenetic factors in anticancer drug resistance.AuthorsShoemaker, Robert H.; Shoemaker, R HAbstractEditorial. Discusses the genetic and epigenetic factors that have been implicated as determinants of anticancer drug resistance. Discovery of the phenomenon of gene amplification; Role of the tumor microenvironment.SubjectsDRUG resistance; ANTINEOPLASTIC agents; GENE amplification; DRUG resistance in cancer cells; GENES; TUMORS; PHARMACODYNAMICSPublicationJNCI: Journal of the National Cancer Institute, 2000, Vol 92, Issue 1, p4ISSN0027-8874Publication typecommentaryDOI10.1093/jnci/92.1.4