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- Title
Efficacy of 90Y ibritumomab-tiuxetan treatment in a case of resistant gastric MALT non-Hodgkin's lymphoma.
- Authors
Ferrucci, P. F.; Vanazzi, A.; Crosta, C.; Pruneri, G.; Grana, C.; Bartolomei, M.; Paganelli, G.; Martinelli, G.
- Abstract
Treatment modalities for resistant/relapsing gastric mucosa associated lymphoid tissue (MALT) non-Hodgkin's lymphoma (NHL) are not yet well standardized. In the past, most patients were treated surgically with a gastrectomy, while, more recently, radiotherapy and systemic approaches (chemotherapy and immunotherapy) have been used with improving results. Here, we report the case of a patient affected by MALT NHL resistant to antibiotics, chemotherapy and immunotherapy, who achieved a durable complete remission after radio-immunotherapy treatment with Zevalin (90Y ibritumomab-tiuxetan), administered in a singlestandard dose. This observation must be confirmed on a larger series but suggests that radio-immunotherapy may be a valid approach in treating relapsing MALT NHL patients, or those resistant to conventional therapies, so avoiding more aggressive and toxic approaches.
- Subjects
MEDICAL research; THERAPEUTICS; GASTRIC mucosa; HODGKIN'S disease; GASTRECTOMY; MEDICAL care; DRUG therapy; IMMUNOTHERAPY; PHOTOTHERAPY; DISEASES
- Publication
Ecancermedicalscience, 2008, Vol 2, p1
- ISSN
1754-6605
- Publication type
Article
- DOI
10.3332/ecancer.2008.79