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Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 5, p. 1945, doi. 10.1172/JCI69592
By:
- Antignano, Frann;
- Burrows, Kyle;
- Hughes, Michael R.;
- Han, Jonathan M.;
- Kron, Ken J.;
- Penrod, Nadia M.;
- Oudhoff, Menno J.;
- Hao Wang, Steven Kai;
- Min, Paul H.;
- Gold, Matthew J.;
- Chenery, Alistair L.;
- Braam, Mitchell J. S.;
- Fung, Thomas C.;
- Rossi, Fabio M. V.;
- McNagny, Kelly M.;
- Arrowsmith, Cheryl H.;
- Mathieu Lupien;
- Levings, Megan K.;
- Zaph, Colby
Publication type:
Article
The histone variant H2A.Z is an important regulator of enhancer activity.
Published in:
Nucleic Acids Research, 2015, v. 43, n. 20, p. 9742, doi. 10.1093/nar/gkv825
By:
- Brunelle, Mylène;
- Markovits, Alexei Nordell;
- Rodrigue, Sébastien;
- Lupien, Mathieu;
- Jacques, Pierre-Étienne;
- Gévry, Nicolas
Publication type:
Article
Variant Set Enrichment: an R package to identify disease-associated functional genomic regions.
Published in:
BioData Mining, 2017, v. 10, p. 1, doi. 10.1186/s13040-017-0129-5
By:
- Ahmed, Musaddeque;
- Sallari, Richard C.;
- Guo, Haiyang;
- Moore, Jason H.;
- Housheng Hansen He;
- Lupien, Mathieu
Publication type:
Article
Des mutations épigénétiques spécifiques aux enhancers sont associées à la carcinogenèse colorectale.
Published in:
Médecine Sciences, 2012, v. 28, n. 11, p. 929, doi. 10.1051/medsci/20122811009
By:
- Brunelle, Mylène;
- Gévry, Nicolas;
- Lupien, Mathieu
Publication type:
Article
Corrigendum: Human somatic cell mutagenesis creates genetically tractable sarcomas.
Published in:
Nature Genetics, 2014, v. 46, n. 12, p. 1372, doi. 10.1038/ng1214-1372
By:
- Molyneux, Sam D;
- Waterhouse, Paul D;
- Shelton, Dawne;
- Shao, Yang W;
- Watling, Christopher M;
- Tang, Qing-Lian;
- Harris, Isaac S;
- Dickson, Brendan C;
- Tharmapalan, Pirashaanthy;
- Sandve, Geir K;
- Zhang, Xiaoyang;
- Bailey, Swneke D;
- Berman, Hal;
- Wunder, Jay S;
- Iszvak, Zsuzsanna;
- Lupien, Mathieu;
- Mak, Tak W;
- Khokha, Rama
Publication type:
Article
Human somatic cell mutagenesis creates genetically tractable sarcomas.
Published in:
Nature Genetics, 2014, v. 46, n. 9, p. 964, doi. 10.1038/ng.3065
By:
- Molyneux, Sam D;
- Waterhouse, Paul D;
- Shelton, Dawne;
- Shao, Yang W;
- Watling, Christopher M;
- Tang, Qing-Lian;
- Harris, Isaac S;
- Dickson, Brendan C;
- Tharmapalan, Pirashaanthy;
- Sandve, Geir K;
- Zhang, Xiaoyang;
- Bailey, Swneke D;
- Berman, Hal;
- Wunder, Jay S;
- Iszvak, Zsuzsanna;
- Lupien, Mathieu;
- Mak, Tak W;
- Khokha, Rama
Publication type:
Article
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression.
Published in:
Nature Genetics, 2012, v. 44, n. 11, p. 1191, doi. 10.1038/ng.2416
By:
- Cowper-Sal·lari, Richard;
- Zhang, Xiaoyang;
- Wright, Jason B;
- Bailey, Swneke D;
- Cole, Michael D;
- Eeckhoute, Jerome;
- Moore, Jason H;
- Lupien, Mathieu
Publication type:
Article
Nucleosome dynamics define transcriptional enhancers.
Published in:
Nature Genetics, 2010, v. 42, n. 4, p. 343, doi. 10.1038/ng.545
By:
- Housheng Hansen He;
- Meyer, Clifford A.;
- Hyunjin Shin;
- Bailey, Shannon T.;
- Gang Wei;
- Qianben Wang;
- Yong Zhang;
- Kexin Xu;
- Min Ni;
- Lupien, Mathieu;
- Mieczkowski, Piotr;
- Lieb, Jason D.;
- Zhao, Keji;
- Brown, Myles;
- X. Shirley Liu
Publication type:
Article
Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo.
Published in:
PLoS Biology, 2018, v. 16, n. 6, p. 1, doi. 10.1371/journal.pbio.2004049
By:
- Sonzogni, Olmo;
- Haynes, Jennifer;
- Seifried, Laurie A.;
- Kamel, Yahia M.;
- Huang, Kai;
- BeGora, Michael D.;
- Yeung, Faith Au;
- Robert-Tissot, Celine;
- Heng, Yujing J.;
- Yuan, Xin;
- Wulf, Gerbug M.;
- Kron, Ken J.;
- Wagenblast, Elvin;
- Lupien, Mathieu;
- Kislinger, Thomas;
- Hannon, Gregory J.;
- Muthuswamy, Senthil K.
Publication type:
Article
Identification of PBX1 Target Genes in Cancer Cells by Global Mapping of PBX1 Binding Sites.
Published in:
PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036054
By:
- Thiaville, Michelle M.;
- Stoeck, Alexander;
- Chen, Li;
- Wu, Ren-Chin;
- Magnani, Luca;
- Oidtman, Jessica;
- Shih, Ie-Ming;
- Lupien, Mathieu;
- Wang, Tian-Li
Publication type:
Article
A chemical toolbox for the study of bromodomains and epigenetic signaling.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09672-2
By:
- Wu, Qin;
- Heidenreich, David;
- Zhou, Stanley;
- Ackloo, Suzanne;
- Krämer, Andreas;
- Nakka, Kiran;
- Lima-Fernandes, Evelyne;
- Deblois, Genevieve;
- Duan, Shili;
- Vellanki, Ravi N.;
- Li, Fengling;
- Vedadi, Masoud;
- Dilworth, Jeffrey;
- Lupien, Mathieu;
- Brennan, Paul E.;
- Arrowsmith, Cheryl H.;
- Müller, Susanne;
- Fedorov, Oleg;
- Filippakopoulos, Panagis;
- Knapp, Stefan
Publication type:
Article
Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09309-4
By:
- Lima-Fernandes, Evelyne;
- Murison, Alex;
- da Silva Medina, Tiago;
- Wang, Yadong;
- Ma, Anqi;
- Leung, Cherry;
- Luciani, Genna M.;
- Haynes, Jennifer;
- Pollett, Aaron;
- Zeller, Constanze;
- Duan, Shili;
- Kreso, Antonija;
- Barsyte-Lovejoy, Dalia;
- Wouters, Bradly G.;
- Jin, Jian;
- Carvalho, Daniel D. De;
- Lupien, Mathieu;
- Arrowsmith, Cheryl H.;
- O'Brien, Catherine A.
Publication type:
Article
The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population.
Published in:
Frontiers in Immunology, 2023, v. 14, p. 01, doi. 10.3389/fimmu.2023.1161901
By:
- Medina, Tiago S.;
- Murison, Alex;
- Smith, Michelle;
- Kinker, Gabriela S.;
- Chakravarthy, Ankur;
- Vitiello, Glauco A. F.;
- Turpin, Williams;
- Shu Yi Shen;
- Yau, Helen L.;
- Sarmento, Olga F.;
- Faubion, William;
- Lupien, Mathieu;
- Silverberg, Mark S.;
- Arrowsmith, Cheryl H.;
- De Carvalho, Daniel D.
Publication type:
Article
ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters.
Published in:
Nature Communications, 2015, v. 6, n. 2, p. 6186, doi. 10.1038/ncomms7186
By:
- Bailey, Swneke D.;
- Zhang, Xiaoyang;
- Desai, Kinjal;
- Aid, Malika;
- Corradin, Olivia;
- Cowper-Sal·lari, Richard;
- Akhtar-Zaidi, Batool;
- Scacheri, Peter C.;
- Haibe-Kains, Benjamin;
- Lupien, Mathieu
Publication type:
Article
Early‐life antibiotic treatment enhances the pathogenicity of CD4<sup>+</sup> T cells during intestinal inflammation.
Published in:
Journal of Leukocyte Biology, 2017, v. 101, n. 4, p. 893, doi. 10.1189/jlb.3MA0716-334RR
By:
- Scheer, Sebastian;
- Medina, Tiago S.;
- Murison, Alex;
- Taves, Matthew D.;
- Antignano, Frann;
- Chenery, Alistair;
- Soma, Kiran K.;
- Perona‐Wright, Georgia;
- Lupien, Mathieu;
- Arrowsmith, Cheryl H.;
- De Carvalho, Daniel D.;
- Zaph, Colby
Publication type:
Article
Antibodies against the PER protein of Drosophila label neurons in the optic lobe, central brain, and thoracic ganglia of the crickets Teleogryllus commodus and Teleogryllus oceanicus.
Published in:
Cell & Tissue Research, 2003, v. 312, n. 3, p. 377, doi. 10.1007/s00441-003-0720-6
By:
- Lupien, Mathieu;
- Marshall, Stephanie;
- Leser, Winrich;
- Pollack, Gerald S.;
- Honegger, Hans-Willi
Publication type:
Article
Publisher Correction: ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/ncomms16194
By:
- Bailey, Swneke D.;
- Xiaoyang Zhang;
- Desai, Kinjal;
- Aid, Malika;
- Corradin, Olivia;
- Cowper-Sal·lari, Richard;
- Akhtar-Zaidi, Batool;
- Scacheri, Peter C.;
- Haibe-Kains, Benjamin;
- Lupien, Mathieu
Publication type:
Article
Publisher Correction: ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters.
Published in:
Nature Communications, 2018, v. 9, p. 16194, doi. 10.1038/ncomms16194
By:
- Bailey, Swneke D.;
- Zhang, Xiaoyang;
- Desai, Kinjal;
- Aid, Malika;
- Corradin, Olivia;
- Cowper-Sal·lari, Richard;
- Akhtar-Zaidi, Batool;
- Scacheri, Peter C.;
- Haibe-Kains, Benjamin;
- Lupien, Mathieu
Publication type:
Article
Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro.
Published in:
2018
By:
- Smirnov, Petr;
- Safikhani, Zhaleh;
- Quevedo, Rene;
- Lupien, Mathieu;
- Mak, Tak W.;
- Haibe-Kains, Benjamin;
- Thu, Kelsie L.;
- Silvester, Jennifer;
- Cescon, David;
- El-Hachem, Nehme
Publication type:
Correction Notice
Gene isoforms as expression-based biomarkers predictive of drug response in vitro.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01153-8
By:
- Safikhani, Zhaleh;
- Smirnov, Petr;
- Thu, Kelsie L.;
- Silvester, Jennifer;
- El-Hachem, Nehme;
- Quevedo, Rene;
- Lupien, Mathieu;
- Mak, Tak W.;
- Cescon, David;
- Haibe-Kains, Benjamin
Publication type:
Article
SMuRF: a novel tool to identify regulatory elements enriched for somatic point mutations.
Published in:
BMC Bioinformatics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12859-018-2501-y
By:
- Guilhamon, Paul;
- Lupien, Mathieu
Publication type:
Article
PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer.
Published in:
PLoS Genetics, 2011, v. 7, n. 11, p. 1, doi. 10.1371/journal.pgen.1002368
By:
- Magnani, Luca;
- Ballantyne, Elizabeth B.;
- Xiaoyang Zhang;
- Lupien, Mathieu
Publication type:
Article
3-D chromatin conformation, accessibility, and gene expression profiling of triple-negative breast cancer.
Published in:
BMC Genomic Data, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12863-023-01166-x
By:
- Llinàs-Arias, Pere;
- Ensenyat-Méndez, Miquel;
- Orozco, Javier I. J.;
- Íñiguez-Muñoz, Sandra;
- Valdez, Betsy;
- Wang, Chuan;
- Mezger, Anja;
- Choi, Eunkyoung;
- Tran, Yan Zhou;
- Yao, Liqun;
- Bonath, Franziska;
- Olsen, Remi-André;
- Ormestad, Mattias;
- Esteller, Manel;
- Lupien, Mathieu;
- Marzese, Diego M.
Publication type:
Article
Pioneer of prostate cancer: past, present and the future of FOXA1.
Published in:
Protein & Cell, 2021, v. 12, n. 1, p. 29, doi. 10.1007/s13238-020-00786-8
By:
- Teng, Mona;
- Zhou, Stanley;
- Cai, Changmeng;
- Lupien, Mathieu;
- He, Housheng Hansen
Publication type:
Article
Detection of metabolic adaptation in a triple-negative breast cancer animal model with [<sup>18</sup>F]choline-PET imaging as a surrogate for drug resistance.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2024, v. 51, n. 5, p. 1261, doi. 10.1007/s00259-023-06546-0
By:
- Kohan, Andres A.;
- Lupien, Mathieu;
- Cescon, David;
- Deblois, Geneviève;
- Ventura, Manuela;
- Metser, Ur;
- Veit-Haibach, Patrick
Publication type:
Article
C3D: a tool to predict 3D genomic interactions between cis-regulatory elements.
Published in:
Bioinformatics, 2019, v. 35, n. 5, p. 877, doi. 10.1093/bioinformatics/bty717
By:
- Mehdi, Tahmid;
- Bailey, Swneke D;
- Guilhamon, Paul;
- Lupien, Mathieu
Publication type:
Article
PharmacoGx: an R package for analysis of large pharmacogenomic datasets.
Published in:
Bioinformatics, 2016, v. 32, n. 8, p. 1244, doi. 10.1093/bioinformatics/btv723
By:
- Smirnov, Petr;
- Safikhani, Zhaleh;
- El-Hachem, Nehme;
- Dong Wang;
- She, Adrian;
- Olsen, Catharina;
- Freeman, Mark;
- Selby, Heather;
- Gendoo, Deena M. A.;
- Grossmann, Patrick;
- Beck, Andrew H.;
- Aerts, Hugo J. W. L.;
- Lupien, Mathieu;
- Goldenberg, Anna;
- Haibe-Kains, Benjamin
Publication type:
Article
ABC: a tool to identify SNVs causing allele-specific transcription factor binding from ChIP-Seq experiments.
Published in:
Bioinformatics, 2015, v. 31, n. 18, p. 3057, doi. 10.1093/bioinformatics/btv321
By:
- Bailey, Swneke D.;
- Virtanen, Carl;
- Haibe-Kains, Benjamin;
- Lupien, Mathieu
Publication type:
Article
Dual Suppression of the Cyclin-Dependent Kinase Inhibitors CDKN2C and CDKN1A in Human Melanoma.
Published in:
JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 21, p. 1673, doi. 10.1093/jnci/djs373
By:
- Jalili, Ahmad;
- Wagner, Christine;
- Pashenkov, Mikhail;
- Pathria, Gaurav;
- Mertz, Kirsten D.;
- Widlund, Hans R.;
- Lupien, Mathieu;
- Brunet, Jean- Philippe;
- Golub, Todd R.;
- Stingl, Georg;
- Fisher, David E.;
- Ramaswamy, Sridhar;
- Wagner, Stephan N.
Publication type:
Article
Estrogen-Dependent Signaling in a Molecularly Distinct Subclass of Aggressive Prostate Cancer.
Published in:
JNCI: Journal of the National Cancer Institute, 2008, v. 100, n. 11, p. 815, doi. 10.1093/jnci/djn150
By:
- Setlur, Sunita R.;
- Mertz, Kirsten D.;
- Hoshida, Yujin;
- Demichelis, Francesca;
- Lupien, Mathieu;
- Perner, Sven;
- Sboner, Andrea;
- Pawitan, Yudi;
- Andrén, Ove;
- Johnson, Laura A.;
- Tang, Jeff;
- Adami, Hans-Olov;
- Calza, Stefano;
- Chinnaiyan, Arul M.;
- Rhodes, Daniel;
- Tomlins, Scott;
- Fall, Katja;
- Mucci, Lorelei A.;
- Kantoff, Philip W.;
- Stampfer, Meir J.
Publication type:
Article
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21233-0
By:
- Mer, Arvind Singh;
- Heath, Emily M.;
- Madani Tonekaboni, Seyed Ali;
- Dogan-Artun, Nergiz;
- Nair, Sisira Kadambat;
- Murison, Alex;
- Garcia-Prat, Laura;
- Shlush, Liran;
- Hurren, Rose;
- Voisin, Veronique;
- Bader, Gary D.;
- Nislow, Corey;
- Rantalainen, Mattias;
- Lehmann, Soren;
- Gower, Mark;
- Guidos, Cynthia J.;
- Lupien, Mathieu;
- Dick, John E.;
- Minden, Mark D.;
- Schimmer, Aaron D.
Publication type:
Article
Large organized chromatin lysine domains help distinguish primitive from differentiated cell populations.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20830-9
By:
- Madani Tonekaboni, Seyed Ali;
- Haibe-Kains, Benjamin;
- Lupien, Mathieu
Publication type:
Article

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