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- Title
Drugs that slow the progression of diabetic kidney disease: are renoprotective effects attenuated in heart failure?
- Authors
Packer, Milton; Siddiqi, Tariq Jamal; Butler, Javed
- Abstract
However, it should be noted that, in large-scale trials of patients with type 2 diabetes, a heightened ratio of heart failure events to end-stage kidney disease is also observed and worsening heart failure events are prevented by active treatment, and yet, angiotensin receptor blockers, ACE inhibitors, mineralo-corticoid receptor antagonists, and SGLT2 inhibitors exert a striking renoprotective effect in diabetic patients. What might explain differences in the results with angiotensin receptor blockers, ACE inhibitors, mineralocorticoid receptor antagonists, and SGLT2 inhibitors in patients with Type 2 diabetes vs. those with heart failure?.
- Subjects
DIABETIC nephropathies; ALDOSTERONE antagonists; SODIUM-glucose cotransporters; HEART assist devices; HEART failure; DRUGS; CENTRAL venous pressure; CHRONIC kidney failure
- Publication
European Heart Journal, 2023, Vol 44, Issue 17, p1522
- ISSN
0195-668X
- Publication type
Article
- DOI
10.1093/eurheartj/ehad158