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- Title
Effects of Oral Glucose Administration on Plasma Biochemical Parameters, Insulin, and Hepatic Metabolic Enzymes Activities in Golden Pompano (Trachinotus ovatus).
- Authors
Chuanpeng Zhou; Heizhao Lin; Zhong Huang; Jun Wang; Yun Wang; Wei Yu
- Abstract
Two doses of glucose (335 and 1670 mg of glucose per kg body weight) were orally administered to golden pompano (Trachinotus ovatus). Plasma glucose and cholesterol level reached its peak 3h after oral administration with high dose of glucose, respectively (P<0.05). Plasma insulin content was significantly lower at 1, 3, 6 and 12 h after oral administration of both doses of glucose (P<0.05). Compared to the low dose of glucose group, the high dose of glucose group has lower plasma glucagon content 12 h after oral administration, higher muscle and hepatic glycogen contents 6 h after oral administration (P<0.05). The hepatic pyruvate kinase activity peaked 6 h after oral administration in both doses of glucose groups and thereafter started to decrease 24 h after oral administration. While the hepatic PEPCK and G6Pase activities decreased 9 h after oral administration in both doses of glucose groups and then returned to the level at 0 h (P<0.05). These results suggested that glucose oral administration resulted in prolonged hyperglycemia and high level of hepatic glycogen in T. ovatus which could lead to nutritional stress, and increasing glucose metabolic burden in this species.
- Subjects
GLUCOSE; INSULIN; PYRUVATE kinase; HYPERGLYCEMIA; TYPE 1 diabetes; DIAGNOSIS
- Publication
Pakistan Journal of Zoology, 2018, Vol 50, Issue 3, p1119
- ISSN
0030-9923
- Publication type
Article
- DOI
10.17582/journal.pjz/2018.50.3.1119.1129