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Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4 <sup>CRBN</sup>.
- Published in:
- British Journal of Haematology, 2014, v. 164, n. 6, p. 811, doi. 10.1111/bjh.12708
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- Article
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.
- Published in:
- Oncogene, 2005, v. 24, n. 7, p. 1138, doi. 10.1038/sj.onc.1208236
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- Article
Differential regulation of TGF-ß signaling through Smad2, Smad3 and Smad4.
- Published in:
- Oncogene, 2003, v. 22, n. 43, p. 6748, doi. 10.1038/sj.onc.1206791
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- Article
Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors.
- Published in:
- Bioscience Reports, 2014, v. 34, n. 2, p. 93, doi. 10.1042/BSR20140010
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- Article
Reciprocal regulation of amino acid import and epigenetic state through Lat1 and EZH2.
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- EMBO Journal, 2015, v. 34, n. 13, p. 1773, doi. 10.15252/embj.201488166
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- Article
Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P<sub>2</sub> to the mSOS pleckstrin homology domain.
- Published in:
- Oncogene, 1998, v. 16, n. 18, p. 2303, doi. 10.1038/sj.onc.1201891
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- Article
Inducible shRNA expression for application in a prostate cancer mouse model.
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- Nucleic Acids Research, 2003, v. 31, n. 21, p. e127, doi. 10.1093/nar/gng127
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- Article
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells.
- Published in:
- Nucleic Acids Research, 2003, v. 31, n. 11, p. 2705, doi. 10.1093/nar/gkg393
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- Publication type:
- Article
Functional studies of the PI(3)‐kinase signalling pathway employing synthetic and expressed siRNA.
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- Nucleic Acids Research, 2003, v. 31, n. 2, p. 670, doi. 10.1093/nar/gkg141
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- Article
Peroxiredoxin 6 is required for blood vessel integrity in wounded skin.
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- Journal of Cell Biology, 2007, v. 179, n. 4, p. 747, doi. 10.1083/jcb.200706090
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- Article
MCT4 is an important determinant for the growth of highly glycolytic and aggressive malignancies.
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- 2012
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- Publication type:
- Abstract
The interaction of PKN3 with RhoC promotes malignant growth
- Published in:
- Molecular Oncology, 2012, v. 6, n. 3, p. 284, doi. 10.1016/j.molonc.2011.12.001
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- Publication type:
- Article