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- Title
The effect of extremely narrow MLC leaf width on the plan quality of VMAT for prostate cancer.
- Authors
Jong Min Park; So-Yeon Park; Jin Ho Kim; Carlson, Joel; Jung-in Kim; Park, Jong Min; Park, So-Yeon; Kim, Jin Ho; Kim, Jung-In
- Abstract
<bold>Background: </bold>To investigate the effect of multi-leaf collimators (MLCs) with leaf width of 1.25 mm on the plan quality of volumetric modulated arc therapy (VMAT) for prostate cancer.<bold>Methods: </bold>A total of 20 patients with prostate cancer were retrospectively selected. Using a high definition MLC (HD MLC), primary and boost VMAT plans with two full arcs were generated for each patient (original plan). After that, by shifting the isocenter position of the 2nd arc by 1.25 mm in the cranio-caudal direction, we simulated fluences made with MLCs with leaf width of 1.25 mm. After shifting, primary and boost plans were generated for each patient (shifted plan). A sum plan was generated by summation of the primary and boost plan for each patient. Dose-volumetric parameters were calculated and compared.<bold>Results: </bold>Both the homogeneity index (HI) and conformity index (CI) of the shifted plans were better than those of the original plans in primary plans (HI = 0.065 vs. 0.059 with p < 0.001 and CI = 1.056 vs. 1.044 with p = 0.006). Similarly, the shifted plans for the boost target volume showed better homogeneity and conformity than did the original plans (HI = 0.060 vs. 0.053 with p < 0.001 and CI = 1.015 vs. 1.009 with p < 0.001). The target mean dose of the original plans was closer to the prescription dose than that of the shifted plans in the case of sum plans (81.45 Gy vs. 81.12 Gy with p = 0.001).<bold>Conclusions: </bold>Use of extremely narrow MLCs could increase dose homogeneity and conformity of the target volume for prostate VMAT.
- Subjects
X-ray collimators; VOLUMETRIC-modulated arc therapy; PROSTATE cancer; RADIOTHERAPY; PHOTON beams; RADIATION therapy equipment; COMPARATIVE studies; RESEARCH methodology; MEDICAL cooperation; COMPUTERS in medicine; IMAGING phantoms; PROSTATE tumors; RADIATION doses; RESEARCH; EVALUATION research; RETROSPECTIVE studies
- Publication
Radiation Oncology, 2016, Vol 11, p1
- ISSN
1748-717X
- Publication type
journal article
- DOI
10.1186/s13014-016-0664-0