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- Title
Association between financial toxicity and health-related quality of life of patients with gynecologic cancer.
- Authors
Kajimoto, Yusuke; Honda, Kazunori; Suzuki, Shiro; Mori, Masahiko; Tsubouchi, Hirofumi; Nakao, Kohshiro; Azuma, Anri; Shibutani, Takashi; Nagao, Shoji; Koyanagi, Takahiro; Kohara, Izumi; Tamaki, Shuko; Yabuki, Midori; Teng, Lida; Fujiwara, Keiichi; Igarashi, Ataru
- Abstract
Objectives: Patients often struggle with their financial situation during cancer treatment due to treatment-related costs or loss of income. This resulting negative effect is called financial toxicity, which is a known as a side effect of cancer care. This study aimed to evaluate the association between financial toxicity and health-related quality of life among patients with gynecologic cancer using validated questionnaires. Methods: In this multicenter study, patients with gynecologic cancer receiving anti-cancer drug treatment for > 2 months were recruited. Patients answered the COmprehensive Score for Financial Toxicity (COST) tool, EORTC-QLQ-C30, disease-specific tools (EORTC-QLQ-OV28/CX24/EN24), and EQ-5D-5L. Spearman's rank correlation coefficient was used to determine associations. Results: Between April 2019 and July 2021, 109 cancer patients completed the COST questionnaire. The mean COST score was 19.82. Strong associations were observed between financial difficulty (r = − 0.616) in the EORTC-QLQ-C30 and body image (r = 0.738) in the EORTC-QLQ-CX24, while weak associations were noted between the global health status/quality of life (r = 0.207), EQ-5D-5L index score (r = 0.252), and several function and symptom scale scores with the COST score. Conclusions: Greater financial toxicity was associated with worse health-related quality of life scores, such as financial difficulty in gynecologic cancer patients and body image in cervical cancer patients as strong associations, and weakly associated with general health-related quality of life scores and several function/symptom scales.
- Subjects
QUALITY of life; GYNECOLOGIC cancer; CANCER patients; FINANCIAL stress; BODY image; CERVICAL cancer
- Publication
International Journal of Clinical Oncology, 2023, Vol 28, Issue 3, p454
- ISSN
1341-9625
- Publication type
Article
- DOI
10.1007/s10147-023-02294-1