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- Title
Stage IVB uterine endometrial cancer successfully salvaged bychemoradiotherapy and surgery.
- Authors
Kaneyasu, Yuko; Okawa, Tomohiko; Yajima, Masazumi; Saito, Rie; Nakabayashi, Masao; Seshimo, Akiyoshi; Kameoka, Shingo; Aomi, Shigeyuki; Nishikawa, Toshio; Sawada, Tatsuo; Mitsuhashi, Norio
- Abstract
A case of stage IVB adenoacanthoma of the uterine corpus is described. The patient was admitted with a large amount of atypical genital bleeding. Computed tomography and magnetic resonance imaging revealed a large tumor accompanied by lymph node involvement in the left inguinal, multiple pelvic, and paraaortic regions. She was diagnosed as having stage IVB endometrial adenoacanthoma. Neoadjuvant chemotherapy with carboplatin (CBDCA) and 5-fluorouracil (5-FU) was performed, followed by radiotherapy. The tumor responded very well, but still remained in Douglas' pouch after treatment. The patient therefore underwent a simple hysterectomy, pelvic and paraaortic lymphadenectomy, and partial rectal resection. Histopathologically, viable cancer cells were observed only in the fundus of the uterus. The patient is alive with no evidence of recurrences 4 years the initiation of chemoradiotheraphy.
- Subjects
DRUG side effects; CANCER treatment; MITOMYCIN C; ANTINEOPLASTIC antibiotics; HEMICOLECTOMY; COLON cancer; CHRONIC myeloid leukemia; ONCOLOGY
- Publication
International Journal of Clinical Oncology, 2003, Vol 8, Issue 1, p60
- ISSN
1341-9625
- Publication type
Article
- DOI
10.1007/s101470300010