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- Title
Spectrum of retinal abnormalities in renal transplant patients using chronic low-dose steroids.
- Authors
Dijk, Elon; Soonawala, Darius; Rooth, Vera; Hoyng, Carel; Meijer, Onno; Vries, Aiko; Boon, Camiel
- Abstract
Purpose: To assess the ophthalmological characteristics of asymptomatic patients with a renal transplant on chronic low-dose steroids for at least the last 2 years prior to examination. Methods: Cross-sectional study. All patients underwent an extensive ophthalmological examination. Results: Of the 37 included patients [25 male, 12 female; 59 ± 11 years (range, 38-77 years)] ophthalmological phenotyping revealed abnormalities in 22 patients (59%). Findings characteristic for (subclinical) central serous chorioretinopathy were detected in ten patients (27%), including two patients with serous subretinal fluid in the macula. An epiretinal membrane of the macula was present in six patients (16%). Mean subfoveal choroidal thickness was significantly increased in patients with ophthalmological abnormalities, in comparison with patients without abnormalities. Conclusions: Retinal abnormalities are common in the majority of renal transplant patients using chronic low-dose steroids. These retinal changes may be associated with the renal disease and/or the effect of chronic steroid use on the choroid and retina.
- Subjects
RETINA abnormalities; KIDNEY transplant patients; STEROIDS; MACULA lutea; DRUG dosage
- Publication
Graefe's Archive of Clinical & Experimental Ophthalmology, 2017, Vol 255, Issue 12, p2443
- ISSN
0721-832X
- Publication type
Article
- DOI
10.1007/s00417-017-3823-6