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- Title
Predictors of immediate bleeding during endoscopic submucosal dissection in gastric lesions.
- Authors
Seong Woo Jeon; Min Kyu Jung; Chang Min Cho; Won Young Tak; Young Oh Kweon; Sung Kook Kim; Yong Hwan Choi
- Abstract
Although there have been several reports regarding complications, especially immediate bleeding, of endoscopic mucosal resection for a gastric neoplasm, little is known about the predictors of complications of endoscopic submucosal dissection (ESD). Thus, this study was performed to evaluate the predictive factors for immediate bleeding during ESD procedures. We analyzed 167 patients with 167 gastric lesions from June 2006 to June 2007. Patient-related variables (age, gender, history of aspirin or anti-platelet agents, triple therapy for H. pylori, and use of a proton pump inhibitor), endoscopic variables (lesion size, location, type, and mucosal ulceration), procedure-related variables (procedure time and volume of submucosal injection), and the pathology diagnosis were evaluated as potential risk factors. The mean age of the patients was 62 years. The mean size of the lesions was 15 mm. The overall en bloc resection rate was 98.2%. Immediate bleeding occurred in 20 out of 167 patients. Delayed bleeding was seen in only three patients within 24 h after the procedure. Older age and the location of the lesions (antrum) were associated with a lower frequency of bleeding ( p = 0.006 and p = 0.007, respectively). On multivariate analysis, an older age (OR 0.931, 95% CI 0.88–0.98) and the location of the lesion (antrum; OR 0.254, 95% CI 0.09–0.69) were significant predictive factors for a successful ESD without bleeding. The results of this study demonstrated that age and lesion location were related to the ESD procedure outcome.
- Subjects
ENDOSCOPIC surgery; HEMORRHAGE; SURGICAL excision; SALICYLIC acid; NONSTEROIDAL anti-inflammatory agents
- Publication
Surgical Endoscopy & Other Interventional Techniques, 2009, Vol 23, Issue 9, p1974
- ISSN
1866-6817
- Publication type
Article
- DOI
10.1007/s00464-008-9988-7