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Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2011, v. 66, n. 10, p. 2350, doi. 10.1093/jac/dkr304
By:
- Habtewold, Abiy;
- Amogne, Wondwossen;
- Makonnen, Eyasu;
- Yimer, Getnet;
- Riedel, Klaus-Dieter;
- Ueda, Nobuhisa;
- Worku, Alemayehu;
- Haefeli, Walter Emil;
- Lindquist, Lars;
- Aderaye, Getachew;
- Burhenne, Jürgen;
- Aklillu, Eleni
Publication type:
Article
Constitutive androstane receptor and pregnane X receptor genotype influence efavirenz plasma concentration and CYP2B6 enzyme activity.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-14032-0
By:
- Petros, Zelalem;
- Habtewold, Abiy;
- Makonnen, Eyasu;
- Aklillu, Eleni
Publication type:
Article
Efficacy and Safety of Antiretroviral Therapy Initiated One Week after Tuberculosis Therapy in Patients with CD4 Counts < 200 Cells/μL: TB-HAART Study, a Randomized Clinical Trial.
Published in:
PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0122587
By:
- Amogne, Wondwossen;
- Aderaye, Getachew;
- Habtewold, Abiy;
- Yimer, Getnet;
- Makonnen, Eyasu;
- Worku, Alemayhu;
- Sonnerborg, Anders;
- Aklillu, Eleni;
- Lindquist, Lars
Publication type:
Article
Evaluation of Patterns of Liver Toxicity in Patients on Antiretroviral and Anti-Tuberculosis Drugs: A Prospective Four Arm Observational Study in Ethiopian Patients.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094271
By:
- Yimer, Getnet;
- Gry, Marcus;
- Amogne, Wondwossen;
- Makonnen, Eyasu;
- Habtewold, Abiy;
- Petros, Zelalem;
- Aderaye, Getachew;
- Schuppe-Koistinen, Ina;
- Lindquist, Lars;
- Aklillu, Eleni
Publication type:
Article
Copy Number Variation of Fc Gamma Receptor Genes in HIV-Infected and HIV-Tuberculosis Co-Infected Individuals in Sub-Saharan Africa.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078165
By:
- Machado, Lee R.;
- Bowdrey, Jennifer;
- Ngaimisi, Eliford;
- Habtewold, Abiy;
- Minzi, Omary;
- Makonnen, Eyasu;
- Yimer, Getnet;
- Amogne, Wondwossen;
- Mugusi, Sabina;
- Janabi, Mohammed;
- Aderaye, Getachew;
- Mugusi, Ferdinand;
- Viskaduraki, Maria;
- Aklillu, Eleni;
- Hollox, Edward J.
Publication type:
Article
Importance of Ethnicity, CYP2B6 and ABCB1 Genotype for Efavirenz Pharmacokinetics and Treatment Outcomes: A Parallel-Group Prospective Cohort Study in Two Sub-Saharan Africa Populations.
Published in:
PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0067946
By:
- Ngaimisi, Eliford;
- Habtewold, Abiy;
- Minzi, Omary;
- Makonnen, Eyasu;
- Mugusi, Sabina;
- Amogne, Wondwossen;
- Yimer, Getnet;
- Riedel, Klaus-Dieter;
- Janabi, Mohammed;
- Aderaye, Getachew;
- Mugusi, Ferdinand;
- Bertilsson, Leif;
- Aklillu, Eleni;
- Burhenne, Juergen
Publication type:
Article
Pharmacogenetic & Pharmacokinetic Biomarker for Efavirenz Based ARV and Rifampicin Based Anti-TB Drug Induced Liver Injury in TB-HIV Infected Patients.
Published in:
PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0027810
By:
- Yimer, Getnet;
- Ueda, Nobuhisa;
- Habtewold, Abiy;
- Amogne, Wondwossen;
- Suda, Akira;
- Riedel, Klaus- Dieter;
- Burhenne, Jürgen;
- Aderaye, Getachew;
- Lindquist, Lars;
- Makonnen, Eyasu;
- Aklillu, Eleni
Publication type:
Article
Plasmodium falciparum and Schistosoma mansoni coinfection and the side benefit of artemether-lumefantrine in malaria patients.
Published in:
Journal of Infection in Developing Countries, 2013, v. 7, n. 6, p. 468, doi. 10.3855/jidc.2658
By:
- Abay, Solomon M.;
- Tilahun, Mulugeta;
- Fikrie, Nigus;
- Habtewold, Abiy
Publication type:
Article
β-defensin Genomic Copy Number Is Associated With HIV Load and Immune Reconstitution in Sub-Saharan Africans.
Published in:
Journal of Infectious Diseases, 2012, v. 206, n. 7, p. 1012, doi. 10.1093/infdis/jis448
By:
- Hardwick, Robert J.;
- Amogne, Wondwossen;
- Mugusi, Sabina;
- Yimer, Getnet;
- Ngaimisi, Eliford;
- Habtewold, Abiy;
- Minzi, Omary;
- Makonnen, Eyasu;
- Janabi, Mohammed;
- Machado, Lee R.;
- Viskaduraki, Maria;
- Mugusi, Ferdinand;
- Aderaye, Getachew;
- Lindquist, Lars;
- Hollox, Edward J.;
- Aklillu, Eleni
Publication type:
Article
CCL3L1 copy number, HIV load, and immune reconstitution in sub-Saharan Africans.
Published in:
BMC Infectious Diseases, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2334-13-536
By:
- Aklillu, Eleni;
- Odenthal-Hesse, Linda;
- Bowdrey, Jennifer;
- Habtewold, Abiy;
- Ngaimisi, Eliford;
- Yimer, Getnet;
- Amogne, Wondwossen;
- Mugusi, Sabina;
- Minzi, Omary;
- Makonnen, Eyasu;
- Janabi, Mohammed;
- Mugusi, Ferdinand;
- Aderaye, Getachew;
- Hardwick, Robert;
- Fu, Beiyuan;
- Viskaduraki, Maria;
- Fengtang Yang;
- Hollox, Edward J.
Publication type:
Article
CCL3L1 copy number, HIV load, and immune reconstitution in sub-Saharan Africans.
Published in:
2013
By:
- Aklillu, Eleni;
- Odenthal-Hesse, Linda;
- Bowdrey, Jennifer;
- Habtewold, Abiy;
- Ngaimisi, Eliford;
- Yimer, Getnet;
- Amogne, Wondwossen;
- Mugusi, Sabina;
- Minzi, Omary;
- Makonnen, Eyasu;
- Janabi, Mohammed;
- Mugusi, Ferdinand;
- Aderaye, Getachew;
- Hardwick, Robert;
- Fu, Beiyuan;
- Viskaduraki, Maria;
- Yang, Fengtang;
- Hollox, Edward J
Publication type:
journal article
Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity.
Published in:
BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-3078-3
By:
- Petros, Zelalem;
- Lee, Ming-Ta Michael;
- Atsushi Takahashi;
- Yanfei Zhang;
- Yimer, Getnet;
- Habtewold, Abiy;
- Amogne, Wondwossen;
- Aderaye, Getachew;
- Schuppe-Koistinen, Ina;
- Taisei Mushiroda;
- Makonnen, Eyasu;
- Michiaki Kubo;
- Aklillu, Eleni
Publication type:
Article
Impact of Population and Pharmacogenetics Variations on Efavirenz Pharmacokinetics and Immunologic Outcomes During Anti-Tuberculosis Co-Therapy: A Parallel Prospective Cohort Study in Two Sub-Sahara African Populations.
Published in:
Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00026
By:
- Mugusi, Sabina;
- Habtewold, Abiy;
- Ngaimisi, Eliford;
- Amogne, Wondwossen;
- Yimer, Getnet;
- Minzi, Omary;
- Makonnen, Eyasu;
- Sudfeld, Christopher;
- Burhenne, Jürgen;
- Aklillu, Eleni
Publication type:
Article
Early or deferred initiation of efavirenz during rifampicin-based TB therapy has no significant effect on CYP3A induction in TB-HIV infected patients.
Published in:
2021
By:
- Aklillu, Eleni;
- Zumla, Alimuddin;
- Habtewold, Abiy;
- Amogne, Wondwossen;
- Makonnen, Eyasu;
- Yimer, Getnet;
- Burhenne, Jürgen;
- Diczfalusy, Ulf
Publication type:
journal article
Long-Term Effect of Rifampicin-Based Anti-TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8-Hydroxy-Efavirenz in Ethiopian Patients.
Published in:
Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1538, doi. 10.1002/jcph.756
By:
- Habtewold, Abiy;
- Aklillu, Eleni;
- Makonnen, Eyasu;
- Amogne, Wondwossen;
- Yimer, Getnet;
- Aderaye, Getachew;
- Bertilsson, Leif;
- Owen, Joel S.;
- Burhenne, Jürgen
Publication type:
Article
HLA-B*57 Allele Is Associated with Concomitant Anti-tuberculosis and Antiretroviral Drugs Induced Liver Toxicity in Ethiopians.
Published in:
Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00090
By:
- Petros, Zelalem;
- Junko Kishikawa;
- Makonnen, Eyasu;
- Yimer, Getnet;
- Habtewold, Abiy;
- Aklillu, Eleni
Publication type:
Article

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