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- Title
SCRAM: a pipeline for fast index-free small RNA read alignment and visualization.
- Authors
Fletcher, Stephen J; Boden, Mikael; Mitter, Neena; Carroll, Bernard J
- Abstract
Summary Small RNAs play key roles in gene regulation, defense against viral pathogens and maintenance of genome stability, though many aspects of their biogenesis and function remain to be elucidated. SCRAM (Small Complementary RNA Mapper) is a novel, simple-to-use short read aligner and visualization suite that enhances exploration of small RNA datasets. Availability and implementation The SCRAM pipeline is implemented in Go and Python, and is freely available under MIT license. Source code, multiplatform binaries and a Docker image can be accessed via https://sfletc.github.io/scram/. Supplementary information Supplementary data are available at Bioinformatics online.
- Subjects
NON-coding RNA; DATA visualization; GENETIC regulation; DNA methylation; GO (Computer program language); PYTHON programming language
- Publication
Bioinformatics, 2018, Vol 34, Issue 15, p2670
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/bty161